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dermatomyositis diagnosis rheumatology dermatology clinical photo differential autoimmune myositis papules rash sign signs antimda5dm antinxp2 antinxp2dm comparison creactiveprotein crp cutaneous
ANTI-MDA5 DERMATOMYOSITIS Cutaneous manifestations: • Periorbital heliotrope (blue-purple) rash with edema • Erythematous rash on the face, or the
shoulders (in a shawl ... interphalangeal joints: Gottron ... papules • Inverse Gottron ... Mechanic's hands #AntiMDA5DM ... #AntiMDA5 #Dermatomyositis
Dermatomyositis A middle-aged man describes progressive difficulty combing his hair and rising from a seated position over
heliotrope rash, 2) shawl ... sign, and 3) Gottron's ... HeliotropeRash #Gottrons
Cutaneous and Systemic Findings in Dermatomyositis Cutaneous Findings: - Heliotrope sign and edema - Nail-fold changes -
V-neck sign or shawl ... sign - Gottron's ... sign - Gottron's
Autoimmune Myositis Necrotizing myopathy is associated with higher CK levels, greater level of muscle weakness, less systemic
heliotrope rash, Shaw ... holster sign, and Gottron's
Dermatomyositis with heliotrope rash, shawl sign, and Gottron's papules A middle-aged man describes progressive difficulty combing his
heliotrope rash, shawl ... sign, and Gottron's ... heliotrope rash, 2) shawl ... sign, and 3) Gottron's ... heliotrope #skinrash #shawl
Gottron's Papules in Dermatomyositis Another classic clue is Gottron's papules which are small grouped flat topped papules
Gottron's Papules ... classic clue is Gottron's ... RashDecisionz #Gottrons
Skin Conditions Associated with Joint Pain Rash • Human parvovirus B19 infection Malar rash • SLE • Human parvovirus B19 infection •
Rheumatic fever Gottron's
Inflammatory Myopathies Dermatomyositis • Onset: Subacute • Pattern: Proximal • CK: Up to 50X ULN • Autoantibodies:
periorbital heliotrope, shawl
Dermatomyositis (DM) and Polymyositis (PM): Pathogenesis and clinical findings Elevated Antinuclear Antibodies: Anti-Jo-1, Anti-OJ, Anti-Mi2, Anti-SRP, Anti-EJ,
red papules -> Gottron
C-REACTIVE PROTEIN Discovered by Tillett & Francis in 1930. First identified as a substance in the serum
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