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diagnosis causes syndrome hematology hyperkalemia hypokalemia nephrology rhabdomyolysis treatment algorithm apml bandemia cbc differentiation druginduced encephalopathy gitelman high low medications
Causes of Hypokalemia - Differential Diagnosis Algorithm Increased Loss - Increased GI Loss - Increased Urinary
Hypokalemia - Differential ... Transcellular Shift ... #Hypokalemia #Differential ... Algorithm #causes #potassium ... #low #pathophysiology
Mechanisms of Drug-Induced Hyperkalemia • Direct renin inhibitor (Aliskiren) • Renin release inhibition (NSAIDs, Beta-Blockers)
• Increased EC shift ... #hyperkalemia #differential ... #diagnosis #pathophysiology ... #pharmacology #potassium
Rhabdomyolysis - Differential Diagnosis and Management Summary Trauma: • Immobilization, Crush iniury, Compartment syndrome, Electrical injury Exertional: •
Rhabdomyolysis - Differential ... Diagnosis and Management ... Dermatomyositis) AKI - Pathophysiology ... Shift of extracellular ... Monitor potassium
Bandemia Overview Normal: < 1% Clinically significant: > 10% Band neutrophils are slightly less mature than segmented neutrophils and
Left Shift: • ... Metamyelocyte (Left Shift ... Neutrophil (Normal) Differential ... #Bandemia #differential ... #pathophysiology
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary Causes of Rhabdomyolysis: • Trauma: - Immobilization - Crush injury - Compartment
Rhabdomyolysis - Differential ... Framework and Management ... Shift of extracellular ... Monitor potassium ... #Diagnosis #Management
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
ATRA treatment Pathophysiology ... initiation • Differential ... APML #diagnosis #management ... #hematology #oncology
Causes of Hyperkalemia - Differential Diagnosis Framework • Cellular Shift: - Exercise
Hyperkalemia - Differential ... Framework • Cellular Shift ... angiotensin inhibitors, meds ... #Hyperkalemia #Differential ... Diagnosis #Causes #potassium
Posterior Reversible Encephalopathy Syndrome (PRES) Overview Clinico-Radiological Syndrome, characterized by: • Headache • Seizures • Altered mental
Etiology: • Pathophysiology ... Reversible course Differential ... Seizures: Treat with AEDs ... Syndrome #diagnosis #management
Gitelman Syndrome Overview What? • Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter • Gitelman's syndrome
Hypokalemia (renal potassium ... ratio 0.5%) Differential ... Supplement: • Potassium ... diagnosis #nephrology #management ... #pathophysiology
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