25 results
Oxyhemoglobin Dissociation Curve 

Left Shift - decreased unloading of O2 at tissue level (i.e.  increased
Curve Left Shift ... - Sickle cell anemia ... Dissociation #Curve #Pathophysiology ... #Left #Right #Shift ... #Differential #
Hypokalemia - Differential Diagnosis Algorithm

Transcellular Shift:
 • Alkalosis
 • ↑ beta-2 adrenergic simulation 
 • Erythropoiesis
Hypokalemia - Differential ... Transcellular Shift ... in pernicious anemia ... • Refeeding syndrome ... Transcellular shifts
Causes of Depressed / Lethargic Newborn - Differential Diagnosis Algorithm
Maternal Related:
 • Drugs (Ex. SSRI)
 •
Lethargic Newborn - Differential ... Respiratory Distress Syndrome ... Sepsis Other: • Anemia ... Lethargic #Newborn #Differential ... Algorithm #Causes #Peds
Bandemia Overview

Normal: < 1%
Clinically significant: > 10%

Band neutrophils are slightly less mature than segmented neutrophils and
Bandemia Overview ... -0/abstract BANDemia ... Degree of bandemia ... bacteremia • Bandemia ... CBC #hematology #pathophysiology
Clinically Important Vitamins and Vitamin Deficiency States
Fat-soluble Vitamins: 
 • Vitamin A - Xerophthalmia, night blindness,
E - Haemolytic anaemia ... Wernicke-Korsakoff syndrome ... paraesthesiae • Folate - Anaemia ... Vitamin B12 - Anaemia ... diagnosis #signs #symptoms
Refeeding Syndrome: Pathogenesis and clinical findings

Patients at Risk of Refeeding Syndrome:
 - Little or no nutritional
Refeeding Syndrome ... Metabolic Acidosis • Shift ... hemolysis - anemia ... #diagnosis #pathophysiology ... #symptoms #signs
Refeeding Syndrome Overview

What Is It?
	• Electrolyte/fluid shifts caused by initiation of nutrition in severely malnourished patient.
Electrolyte/fluid shifts ... • These shifts ... overload) Other Symptoms ... #Nutrition #Differential ... #Diagnosis #Pathophysiology
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
Cold Agglutinin Syndrome ... of anemia include ... • hemolytic anemia ... younger pts) Differential ... disease #hemolytic #anemia
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
blood cell count (anemia ... • Aplastic Anemia ... Megaloblastic Anemia ... Myelophthisic Anemia ... dyserythropoietic anemia
Elevated Lactate Dehydrogenase (LDH) - Differential Diagnosis Framework

LDH is a cytoplasmic enzyme present in tissues throughout
Dehydrogenase (LDH) - Differential ... Microangiopathic hemolytic anemia ... - Pernicious anemia ... • Tumor lysis syndrome ... associated with any symptoms