17 results
Liver Enzymes (LFTs) - Causes of Hepatocellular and Cholestatic Liver Injury
Hepatocellular Liver Injury
 • AST/ALT elevation
Liver Enzymes (LFTs ... ) - Causes of Hepatocellular ... + ULN ALT) / (alkaline ... phosphatase + ULN alkaline ... #differential #hepatology
Alkaline Phosphatase (ALP) Elevation - Differential Diagnosis Algorithm

ALP:
 - Enzymes that catalyze hydrolysis of organic phosphate
Differential Diagnosis Algorithm ... disturbance (obstructed liver ... Highest • Bone • Liver ... Intestine - Other causes ... #hepatology
Hepatocellular Liver Injury - Differential Diagnosis Framework:
Liver Injury → liver test abnormalities without evidence of liver
compared with alkaline ... • Infections: Hepatitis ... Differential #Diagnosis #hepatology ... #algorithm #Transaminitis ... #LFTs #hepatitis
Low Alkaline Phosphatase - Hypophosphatasia 

Is Low Alkaline Phosphatase Of Clinical Importance?

ALP enzyme- Discovered in 1923
Low
synthesized in: liver ... • recurrent fractures ... Hyperlipidemia - Hypercalcemia ... pain - Frequent fractures ... Hyophosphatasia #hepatology
Elevated Liver Enzymes - Differential Diagnosis Algorithm
Severe ALT > 15x ULN
 • Viral
 • Drugs/Toxins
 •
Elevated Liver Enzymes ... Differential Diagnosis Algorithm ... • Alcoholic hepatitis ... Others #LFTs #Hepatology ... #Causes
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
Differential Diagnosis Algorithm ... Vascular Causes ... #injury #hepatitis ... differential #diagnosis #algorithm ... #hepatology
Hepatomegaly - Differential Diagnosis Algorithm
Malignant
 • Primary Carcinoma
 • Metastases
 • Lymphoma
 • Leukemia
 • Polycythemia
Differential Diagnosis Algorithm ... Non-Malignant • Fatty Liver ... Infectious • Hepatitis ... Differential #Diagnosis #Algorithm ... #Causes #Hepatology
Causes of Acute Liver Injury - Differential Diagnosis
Hepatocellular - Liver Parenchyma
 • Infectious: Hepatitis C, A,
Causes of Acute ... • Infectious: Hepatitis ... Differential #Diagnosis #Causes ... #Acute #algorithm ... #hepatology
Chronic Hepatitis B - Diagnosis and Management Algorithm

• Who to treat: Essentially treat the pts with
Chronic Hepatitis ... and Management Algorithm ... inflammation (decr ALT ... #HBV #Algorithm ... Management #Treatment #Hepatology
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
Acute Fatty Liver ... hepatocytes → Liver ... = nonspecific (nausea ... Diagnosis: Viral Hepatitis ... Pregnancy #hepatology