9 results
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
Differential Diagnosis Algorithm ... Vascular Causes ... HBV, HCV, HEV, EBV ... intestines, white blood ... #hepatology
Causes of Acute Liver Injury - Differential Diagnosis
Hepatocellular - Liver Parenchyma
 • Infectious: Hepatitis C, A,
Causes of Acute ... C, A, E, B, D, EBV ... Differential #Diagnosis #Causes ... #Acute #algorithm ... #hepatology
Elevated Liver Enzymes - Differential Diagnosis Algorithm
Severe ALT > 15x ULN
 • Viral
 • Drugs/Toxins
 •
Elevated Liver Enzymes ... Differential Diagnosis Algorithm ... • Alcoholic hepatitis ... Others #LFTs #Hepatology ... #Causes
Hepatocellular Liver Injury - Differential Diagnosis Framework:
Liver Injury → liver test abnormalities without evidence of liver
• Infections: Hepatitis ... A/B/C/D/E, EBV, ... Differential #Diagnosis #hepatology ... #algorithm #Transaminitis ... #LFTs #hepatitis
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm
DILI suspicion
Features toxic aetiology: Skin involvement, Kidney injury,
Stepwise Diagnosis Algorithm ... for alternative causes ... HBV, HCV, HEV, EBV ... • Autoimmune hepatitis ... #hepatology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
plateletcount), peripheral blood ... : INR/PT, aPTT(liver ... not required in all ... When do you do a BM ... #Workup #hematology
Low Alkaline Phosphatase - Hypophosphatasia 

Is Low Alkaline Phosphatase Of Clinical Importance?

ALP enzyme- Discovered in 1923
Low
synthesized in: liver ... • recurrent fractures ... deficiency • blood ... Hyperlipidemia - Hypercalcemia ... Hyophosphatasia #hepatology
Major Clinical Trials and Evidence Summary for Transfusion Thresholds in Critical Care

TRICC - NEJM 1999 -
Blood saves lives ... unnecessary and cause ... ALI is the deadliest ... /vmoitra) #EBM ... Transfusion #Thresholds #Hematology
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4)

Work-up of an Elevated Globulin Gap:
•
Castleman disease • AL ... acute HIV, HBV, EBV ... Sarcoidosis) • Liver ... gastric tumors • Hematology ... differential #diagnosis #hematology