11 results
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines

ACLF = possibly reversible condition in those with CLD (± cirrhosis)
those with CLD (± cirrhosis ... Alcohol-Associated Hepatitis ... (DILI) Viral Hepatitis ... #Hepatology #gastroenterology ... #management #diagnosis
Elevated Liver Function Tests (LFTs) - Differential Diagnosis Framework
Mild (<100-500): 
 • NAFLD
 • Cirrhosis
 •
Function Tests (LFTs ... • NAFLD • Cirrhosis ... Chronic Viral Hepatitis ... • Acute Viral Hepatitis ... #hepatology #transaminitis
Patterns of Liver Injury
Transaminase Levels:
  > 50x normal - Ischemic Hepatitis
  > 20x normal
- Acute Viral Hepatitis ... , Toxic Hepatitis ... CMV), Alcoholic cirrhosis ... #LFTs #transaminitis ... #differential #diagnosis
Hepatomegaly - Differential Diagnosis Algorithm
Malignant
 • Primary Carcinoma
 • Metastases
 • Lymphoma
 • Leukemia
 • Polycythemia
Infectious • Hepatitis ... • Alcoholic Hepatitis ... • Autoimmune Hepatitis ... • Drug Induced Hepatitis ... Primary Biliary Cirrhosis
Chronic Hepatitis B - Diagnosis and Management Algorithm

• Who to treat: Essentially treat the pts with
Chronic Hepatitis ... Management Algorithm ... serologic evidence of hepatitis ... Chronic Hepatitis ... #Diagnosis #Management
Elevated Liver Enzymes - Differential Diagnosis Algorithm
Severe ALT > 15x ULN
 • Viral
 • Drugs/Toxins
 •
- Differential Diagnosis ... Algorithm Severe ... • Alcoholic hepatitis ... Infiltrative • Cirrhosis ... • Others #LFTs
Hepatocellular Liver Injury - Differential Diagnosis Framework:
Liver Injury → liver test abnormalities without evidence of liver
- Differential Diagnosis ... • Infections: Hepatitis ... #hepatology #algorithm ... Transaminitis #LFTs ... #hepatitis
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
Check Acute viral hepatitis ... Check Acute viral hepatitis ... Chronic viral hepatitis ... : < 1 • Cirrhosis ... liver #chemistry #diagnosis
Alcoholic Hepatitis - Summary Overview
- Epidemiology
- Pathophysiology
- Clinical Features
- Labs
- Diagnosis
- Differential Diagnosis
- Treatment

Sarah Onorato @sonorato11

#Alcoholic
Alcoholic Hepatitis ... - Differential Diagnosis ... #Alcoholic #Hepatitis ... #hepatology #diagnosis ... #algorithm #management
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
Autoimmune: Autoimmune hepatitis ... Chronic viral hepatitis ... : < 1 • Cirrhosis ... liver #injury #hepatitis ... #algorithm #hepatology