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diagnosis liver differential lfts transaminitis treatment chronic hbv hepatitisb indications aclf aih albumin alcoholic autoimmune causes chemistry dili druginduced failure
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines ACLF = possibly reversible condition in those with CLD (± cirrhosis)
Acute-on-Chronic ... those with CLD (± cirrhosis ... Drug-Induced Liver Injury ... (DILI) Viral Hepatitis ... #Hepatology #gastroenterology
Patterns of Liver Injury Transaminase Levels: > 50x normal - Ischemic Hepatitis > 20x normal
Patterns of Liver Injury ... > 20x normal - Acute ... CMV), Alcoholic cirrhosis ... Patterns #Liver #Injury ... #hepatology #LFTs
Elevated Liver Function Tests (LFTs) - Differential Diagnosis Framework Mild (<100-500): • NAFLD • Cirrhosis •
• NAFLD • Cirrhosis ... Hepatopathy • Acute ... Viral Hepatitis ... Drug-induced liver injury ... Differential #Diagnosis #hepatology
Causes of Acute Liver Injury - Differential Diagnosis Hepatocellular - Liver Parenchyma • Infectious: Hepatitis C, A,
Causes of Acute ... Liver Injury - Differential ... , Acute biliary ... Sophia_Hayes_MD #Liver #Injury ... #algorithm #hepatology
Indications for Albumin for Management of Cirrhosis • Large volume paracentesis (>5 liter) - 8g per
for Albumin for Management ... of Cirrhosis ... ascites removed • Acute ... kidney injury ( ... #hepatology
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
Acute Liver Injury ... Differential Diagnosis Algorithm ... : < 1 • Cirrhosis ... #diagnosis #algorithm ... #hepatology
Hepatitis B - Treatment Indications Treatment not indicated: • Immune tolerant state - HBe-Ag detectable, high HBV
Hepatitis B - Treatment ... with severe liver injury ... > 3 mg/dL) or acute ... #Indications #management ... #hepatology
Chronic Hepatitis B - Diagnosis and Management Algorithm • Who to treat: Essentially treat the pts with
Diagnosis and Management ... Algorithm • ... viremia or have cirrhosis ... #HBV #Algorithm ... #Treatment #Hepatology
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm DILI suspicion Features toxic aetiology: Skin involvement, Kidney injury,
Stepwise Diagnosis Algorithm ... dechallenge • Acute ... • Autoimmune hepatitis ... #Diagnosis #Algorithm ... #hepatology
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
viral hepatitis ... viral hepatitis ... Chronic viral hepatitis ... : < 1 • Cirrhosis ... #differential #Hepatology
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