16 results
Hypereosinophilia and Hypereosinophilic Syndrome

 • Secondary Hypereosinophilic Syndrome
 • Clinically Relevant HES Variants
 • When to
Syndrome • Secondary ... disorders • Diagnosis ... Syndrome #HES #Hematology ... eosinophils #diagnosis #management ... #algorithm
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
purple, hemorrhagic skin ... leakage of RBC's secondary ... Thrombocytopenia: ITP • Secondary ... Differential #Diagnosis #hematology ... #rheumatology #
Eosinophil Disorders Testing Algorithm
INDICATIONS FOR TESTING:
 • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
Eosinophil Disorders ... Testing Algorithm ... • Screen for secondary ... symptoms (eg, skin ... #diagnosis #hematology
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Headache, Movement disorders ... , Seizure disorders ... APS), Secondary ... CNS #neurology #rheumatology ... cerebritis #diagnosis #management
Cryofibrinogenemia Summary

Cryofibrinogenemia Epidemiology:
 • 40-70 years with a modest female predominance

Cryofibrinogenemia:
 • The precipitation of a
Vascular reactivity (Skin ... cryoglobulinemia Associated Disorders ... Warfarin-induced skin ... Cryofibrinogenemia #diagnosis #rheumatology ... #hematology
Hair Loss (Alopecia) - General (Diffuse and Focal) Differential Diagnosis Algorithm

DIFFUSE
Scarring - Irreversible-biopsy required
 • Lupus
Differential Diagnosis Algorithm ... decalvans - Secondary ... to Skin Disease ... Congenital hair shaft ... areata • Secondary
Cryoglobulinemia Summary

Cryoglobulins:
 • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
- Purpura - Skin ... hematological disorders ... reticularis & skin ... Type III Often Secondary ... classification #rheumatology
Causes of Petechial Rash - Differential Diagnosis Algorithm

Pinpoint areas (less than 2 mm) of hemorrhage, which
Differential Diagnosis Algorithm ... in primary or secondary ... Vasculitis - Collagen disorders ... cryoglobulins • Skin ... #Causes #dermatology
SAPHO Syndrome Summary

What?
SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
chronic inflammatory disorder ... Autoinflammatory disorder ... SAPHO #Syndrome #Rheumatology ... #diagnosis #management ... #Dermatology
Hypereosinophilia Syndrome (HES) - Diagnosis and Management
Definition: An absolute eosinophil count (AEC) greater than 1500 and
Diagnosis and Management ... blood eosinophilia Secondary ... - Immunologic disorders ... eosinophilia #diagnosis #hematology ... #differential #management