12 results
Causes of Anemia with Normal Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Decreased WBCs
 - Decreased/NormaI
Differential Diagnosis Algorithm ... Reticulocytosis • Primary ... Hypersplenism • Secondary ... Differential #Diagnosis #Algorithm ... #Causes #Hematology
Causes of Thrombocytosis - Differential Diagnosis Algorithm
Spurious:
 • Artifact (redo CBC)
Autonomous:
 • Essential thrombocytosis
 • Polycythemia
Artifact (redo CBC ... Myelogenous Leukemia • Primary ... disorders • Celiac disease ... Iron deficiency anemia ... #Causes #Hematology
Pruritus - Generalized Differential Diagnosis Algorithm - Systemic and Primary Causes
== Primary Skin Lesions ==
Macules /
Differential Diagnosis Algorithm ... renal failure/uremia ... Hyperthyroidism CBC ... #secondary #systemic ... #generalized #dermatology
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
purple, hemorrhagic skin ... leakage of RBC's secondary ... /Quantity: • Primary ... - Hemolytic anemia ... Differential #Diagnosis #hematology
Pruritus - No Primary Skin Lesion - Differential Diagnosis Algorithm

Blood Glucose:
 • Diabetes Mellitus
Liver Function Tests/Enzymes:
Pruritus - No Primary ... Skin Lesion - Differential ... renal failure/uremia ... Hyperthyroidism CBC ... #Pruritus #secondary
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
15% of AIHA Primary ... Secondary Cold ... lymphoproliferative disorder Secondary ... Blood smear - RBC ... #hematology #diagnosis
Paraproteinemias

Entities That Can Feature A Monoclonal Protein/M Component:
• MM
• WM
• MGUS
• MGCS
• MGRS
• Splenic Marginal Zone
Entities That Can Feature ... Alpha & Mu) Skin ... (-) hemolytic anemia ... Paraproteinemias #Hematology ... Differential #Diagnosis #Oncology
Polycythemia - Differential Diagnosis Algorithm
Polycythemia itself isn’t a diagnosis. Like many things, it is a condition
Differential Diagnosis Algorithm ... Better call hematology ... else is driving RBC ... As with many disease ... #workup #hematology
Low Alkaline Phosphatase - Hypophosphatasia 

Is Low Alkaline Phosphatase Of Clinical Importance?

ALP enzyme- Discovered in 1923
Low
• recurrent fractures ... pain • loss of secondary ... Malnutrition • Wilson's disease ... • Pernicious anemia ... Hyophosphatasia #hepatology
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
Hepatomegaly • Skin ... cells can indicate disease ... • Neutropenia, anemia ... diagnosis #workup #oncology ... #hematology