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diagnosis differential pancytopenia oncology alkaline causes disorders hemeonc hemophagocytic hlh hyophosphatasia leukemia lymphohistiocytosis management mentzerindex myelodysplasia myelodysplastic phosphatase platelet polycythemia
Pancytopenia - Workup and Differential Diagnosis Algorithm Consumption Disorders 1. Autoimmune Mediated Pancytopenia 2. Splenic Sequestration Peripheral Destruction
Production - Flow ... Acquired Aplastic Anemia ... • Hypoplastic MDS ... Primary hematological ... #Hematology
Pancytopenia - Workup and Differential Diagnosis Algorithm Consumption Disorders 1. Autoimmune Mediated Pancytopenia 2. Splenic Sequestration Peripheral Destruction
Production - Flow ... Acquired Aplastic Anemia ... • Hypoplastic MDS ... Primary hematological ... #Hematology
Low Alkaline Phosphatase - Hypophosphatasia Is Low Alkaline Phosphatase Of Clinical Importance? ALP enzyme- Discovered in 1923 Low
in 1923 Low ALP ... pain • loss of secondary ... • Pernicious anemia ... , ↓ALP → Low ... Hyophosphatasia #hepatology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
Diagnosis and Workup ... changes), high MCV anemia ... not required in all ... unclear, or if a primary ... #hematology
Hematology Algorithms Anemia is described as a reduction in the proportion of the red blood cells.
Hematology Algorithms ... Pancytopenia is a hematologic ... a decrease in all ... Leukopenia is primarily ... Satyendra Dhar MD
Polycythemia - Differential Diagnosis Algorithm Polycythemia itself isn’t a diagnosis. Like many things, it is a condition
Differential Diagnosis Algorithm ... Better call hematology ... else is driving RBC ... levels: realllly low ... #workup #hematology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
formed or don’t work ... just beneath the skin ... DDX: Rule Out Secondary ... Workup: • Complete ... Syndromes #diagnosis #hematology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
- infiltrates (anemia ... + distinctive primary ... bone marrow and secondary ... CLL -> Invade Skin ... #Leukemia #Hematology
Hemophagocytic Lymphohistiocytosis (HLH) High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
Types of HLH • Primary ... STX11, STXBP2 • Secondary ... - Cytopenias (anemia ... Low/absent NK-cell ... Diagnosis #Management #Hematology
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