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diagnosis differential causes oncology pancytopenia dermatology generalized pruritus systemic workup leukemia management mcv mentzerindex myelodysplasia myelodysplastic normocytic rdw reticulocytes syndromes
Causes of Anemia with Normal Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Decreased WBCs - Decreased/NormaI
Differential Diagnosis Algorithm ... • Marrow Aplasia ... Reticulocytosis • Primary ... Hypersplenism • Secondary ... #Causes #Hematology
Algorithmic Approach to Anemia - Differential Diagnosis Framework by MCV Microcytic (MCV < 80) "TAILS": • Thalassemia
Algorithmic Approach ... Non-hemolytic: ACD, Aplastic ... Spherocytosis, G6PD, PK, HbC ... #MCV #Algorithm ... Differential #Diagnosis #hematology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Aplastic Anemia ... • Aplastic anemia ... Headaches • Pale skin ... • ↓ WBC • ↓ ... #hematology #diagnosis
Pancytopenia - Workup and Differential Diagnosis Algorithm Consumption Disorders 1. Autoimmune Mediated Pancytopenia 2. Splenic Sequestration Peripheral Destruction
FISH • Acquired Aplastic ... Anemia • Hypoplastic ... MDS • Congenital ... Primary hematological ... #Hematology
Pruritus - Generalized Differential Diagnosis Algorithm - Systemic and Primary Causes == Primary Skin Lesions == Macules /
Differential Diagnosis Algorithm ... renal failure/uremia ... Hyperthyroidism CBC ... #secondary #systemic ... #generalized #dermatology
Pancytopenia - Workup and Differential Diagnosis Algorithm Consumption Disorders 1. Autoimmune Mediated Pancytopenia 2. Splenic Sequestration Peripheral Destruction
FISH • Acquired Aplastic ... Anemia • Hypoplastic ... MDS • Congenital ... Primary hematological ... #Hematology
Hematology Algorithms Anemia is described as a reduction in the proportion of the red blood cells.
Hematology Algorithms ... RBC are produced ... Pancytopenia is a hematologic ... Leukopenia is primarily ... Satyendra Dhar MD
Pruritus - No Primary Skin Lesion - Differential Diagnosis Algorithm Blood Glucose: • Diabetes Mellitus Liver Function Tests/Enzymes:
Pruritus - No Primary ... Skin Lesion - Differential ... renal failure/uremia ... Hyperthyroidism CBC ... #Pruritus #secondary
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
just beneath the skin ... DDX: Rule Out Secondary ... • Aplastic Anemia ... characteristic feature ... Syndromes #diagnosis #hematology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
- infiltrates (anemia ... + distinctive primary ... bone marrow and secondary ... CLL -> Invade Skin ... #Leukemia #Hematology
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