25 results
Systemic Sclerosis (Scleroderma)
Multi-system autoimmune disease characterized by vasculopathy and progressive fibrosis of skin and internal organs
3
thickening Signs and Symptoms ... Raynaud's, digital ulcers ... Scleroderma #SSc #rheumatology ... #diagnosis #signs ... #symptoms #testing
Systemic Sclerosis Associated Autoantibodies
Anti-topoisomerase I (anti-Sc170): Diffuse skin disease, Pulmonary fibrosis
Anti-centromere: Limited skin disease (~93-95%), Pulmonary
Systemic Sclerosis ... hypertension, Digital ulcers ... BCM_InternalMed #Systemic ... Autoantibodies #diagnosis ... #rheumatology
Indolent Systemic Mastocytosis (ISM)

 • Introduction and Diagnosis
 • Diagnostic Algorithm and Risk Stratification
 • Symptoms
Indolent Systemic ... Algorithm and Risk ... and Symptom Management ... @ZhuoerXie #Systemic ... #SM #Indolent #hematology
Rheumatologic Review of Systems (ROS): 
•	Fevers
•	Rashes/photosensitivity
•	Alopecia
•	Nail/nailfold abnormalities
•	Sicca symptoms
•	Conjunctivitis
•	Uveitis
•	Episcleritis
•	Scleritis
•	Raynaud's
•	Oral/genital ulcers
•	Polychondritis
•	Enthesitis
•	Serositis sx
•	Thomboses
•	Neuropathy
•	Pregnancy loss.

#Rheumatologic #rheumatology #ROS #ReviewOfSystems #diagnosis #history
of Systems (ROS ... abnormalities • Sicca symptoms ... • Oral/genital ulcers ... rheumatology #ROS ... ReviewOfSystems #diagnosis
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Clinical Features of Systemic ... Sjögrens (15%) Skin ... joints Nervous system ... erythematosus #signs #symptoms ... #diagnosis #rheumatology
Systemic Lupus Erythematosus - Diagnosis
Manifestations:
 - Arthritis 69%
 - Malar rash 40%
 - Fever 36%
 -
Systemic Lupus Erythematosus ... Nephropathy 16% - Oral ulcers ... Lupusreference #SLE #Systemic ... autoantibodies #signs #symptoms ... #differential #rheumatology
Eosinophil Disorders Testing Algorithm
INDICATIONS FOR TESTING:
 • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
Disorders Testing Algorithm ... workup for specific symptoms ... (eg, skin or esophageal ... #Differential #diagnosis ... #hematology #eosinophilia
Systemic Lupus Erythematosus (SLE) - Typical Signs/Symptoms
Alopecia, Fever, Malar rash, Photosensitivity, Adenopathies, Lupus pneumonia, Pleurisy, Pancreatitis,
Systemic Lupus Erythematosus ... Typical Signs/Symptoms ... Neuropsychiatric lupus, Oral ulcers ... Lupusreference #Systemic ... #diagnosis #rheumatology
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
Behçet's Syndrome Systemic ... response to local skin ... meningitis), MCC CNS symptoms ... management #signs #symptoms ... #rheumatology #
Cryofibrinogenemia Summary

Cryofibrinogenemia Epidemiology:
 • 40-70 years with a modest female predominance

Cryofibrinogenemia:
 • The precipitation of a
Cryofibrinogenemia Symptoms ... processes: • Systemic ... sensitivity • Painful ulcers ... #rheumatology # ... hematology