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diagnosis rheumatology differential dermatology signs symptoms alopecia arthritis behcet behcets causes conditions criteria cryofibrinogenemia cryoglobulinemia cryoglobulins cutaneous diffuse erythematosus extrarticular
Vasculitis Involving the Skin - Differential Diagnosis Framework Primary: 50% Cutaneous Vasculitis: Leukocytoclastic Vasculitis Secondary: CTD: SLE, RA
the Skin - Differential ... nodules, Deep ulcers ... : • Behcet Disease ... • Cogan syndrome ... #skin #dermatology
Behcet's Syndrome - Diagnosis Diagnostic Criteria for Behget's Syndrome (International Study Group for Behget's Disease): • Recurrent,
Uveitis or retinal vasculitis ... - Skin lesions ... Wide variety of skin ... uveitis, retinal vasculitis ... #criteria #rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
livedo reticularis, ulcers ... : • Behçet Syndrome ... genital aphthous ulcers ... • Cogan Syndrome ... #classification
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
, small-vessel vasculitis ... response to local skin ... recurrent oral ulcers ... test (this is a skin ... signs #symptoms #rheumatology
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
- Purpura - Skin ... ulcers - Glomerulonephritis ... • Autoimmune diseases ... diagnosis #types #classification ... #rheumatology #
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
livedo reticularis, ulcers ... purpura, nodules or ulcers ... • Behcet syndrome ... genital aphthous ulcers ... • Cogan syndrome
Extra-articular and Other Conditions Associated with Joint Pain Eyes • Iritis or uveitis - Spondyloarthropathies, Sarcoidosis,
, Vasculitis (e.g ... Scrotal or vulvar ulcers ... ENT • Oral ulcers ... Scleroderma Thickened skin ... differential #diagnosis #rheumatology
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
Entities That Can Feature ... • Heavy Chain disease ... Alpha & Mu) Skin ... thrombosis+Pulm HTN+skin ... Paraproteinemias #Hematology
Cryofibrinogenemia Summary Cryofibrinogenemia Epidemiology: • 40-70 years with a modest female predominance Cryofibrinogenemia: • The precipitation of a
malignancies, vasculitis ... sensitivity • Painful ulcers ... • Skin necrosis ... Antiphospholipid syndrome ... #hematology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
3rd Decade Skin ... Disease Classification ... Malignancy (e.g. hematologic ... Seizures • Strokes Skin ... vein thrombosis Hematologic
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