11 results
Skin Conditions Associated with Joint Pain

Rash
	• Human parvovirus B19 infection

Malar rash
	• SLE
	• Human parvovirus B19 infection
	•
Joint Pain Rash ... infection Malar rash ... Henoch Schönlein purpura ... lesions • Discoid lupus ... differential #diagnosis #rheumatology
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Clinical Features ... of Systemic Lupus ... Photosensitivity, Butterfly rash ... , Vasculitis, Purpura ... symptoms #diagnosis #rheumatology
Causes of Petechial Rash - Differential Diagnosis Algorithm

Pinpoint areas (less than 2 mm) of hemorrhage, which
Differential Diagnosis Algorithm ... Infection - Vasculitis ... : - Purpura fulminans ... (lupus, RA, Sjogren's ... #Causes #dermatology
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA)

Skin involvement in granulomatosis with polyangiitis (GPA) is common and
Rarely dominate the clinical ... Maculopapular rash ... Polyangiitis #GPA #dermatology ... #rash #diagnosis ... #rheumatology
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary
 • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Systemic Lupus Erythematosus ... 40, F:M 9:1 • Clinical ... Manifestations: Malar rash ... Photosensitivity, Alopecia ... Management #Summary #rheumatology
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
) Suspect: Clinical ... and permanent alopecia ... Non-autoimmune rheumatologic ... • Nonscarring alopecia ... Erythematosus #Diagnosis #Rheumatology
Rapidly Progressive Glomerulonephritis (RPGN)
RPGN has three primary pathophysiologic causes differentiated by immunofluorescence

Immune Complex Mediated (granular staining):
Post-strep GN, Lupus ... Henoch-SchonIein Purpura ... Glomerulonephritis #Vasculitis ... differential #diagnosis #algorithm ... #rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
: • Purpura, ischemic ... inflammation Others: • Lupus ... mucositis - Rash ... such as systemic lupus ... differential #diagnosis #rheumatology
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
to 1:1 F:M • Clinical ... NPSLE rare, Malar rash ... 40, F:M 9:1 • Clinical ... Photosensitivity, Alopecia ... comparison #table #rheumatology
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
disease • Systemic lupus ... rash) • Heart, ... SJIA], systemic lupus ... Diagnosis #Management #Hematology ... #Rheumatology