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management treatment nephrology differential causes medications algorithm binding hypokalemia rhabdomyolysis agents blood druginduced effects evaluation familial hematology high hypertension inheritable
Key Characteristics of Old and New Potassium-Binding Agents - Dr. Edgar V. Lerma https://twitter.com/edgarvlermamd #Potassium #Binding #KBinders #Kayexelate
edgarvlermamd #Potassium ... #Binding #KBinders ... #Kayexelate #Comparison ... #Table #Pharmacology ... #Patiromer #HyperKalemia
Potassium Binders for Management of Hyperkalemia • SPS - Sodium polystyrene sulfonate • Patiromer (veltassa) •
Potassium Binders ... Management of Hyperkalemia ... #Hyperkalemia # ... treatment #pharmacology ... #table #comparison
Potassium-Binding Agents to Treat Hyperkalemia Sodium zirconium cyclosilicate (Lokelma): • Mechanism: Preferentially captures K in exchange for
Potassium-Binding ... of aspiration #Potassium ... #medications #pharmacology ... #table #comparison ... #binders
Mechanisms of Drug-Induced Hyperkalemia • Direct renin inhibitor (Aliskiren) • Renin release inhibition (NSAIDs, Beta-Blockers)
• Increased EC ... shift of K (Succinylcholine ... #differential #diagnosis ... pathophysiology #pharmacology ... #potassium #medications
Hyperkalemia - Management Algorithm • IV calcium • IV insulin and glucose and/or salbutamolt • Consider
Hyperkalemia - Management ... • Consider K+ binder ... and ECG changes ... blocks, QRS axis shift ... #diagnosis #management
Pocket Comparison Guide to Heritable Hypertension Syndromes (Secondary Hypertension) Bartter, Gitelman, Liddle, Primary Aldosteronism, GRA (Glucocorticoid Remediable
Pocket Comparison ... Gordon (Familial Hyperkalemic ... Aldosterone, Cortisol, Potassium ... Hypertension #Syndromes #Comparison ... #Table #Diagnosis
Causes of Hypokalemia Hypokalemia results from abnormal losses, transcellular shifts, or insufficient intake (Table 1).6–8 Abnormal losses
Causes of Hypokalemia ... transcellular shifts ... insufficient intake (Table ... significantly lower potassium ... hospitalized patients #Diagnosis
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 Medications for the Treatment of Hyperkalemia The goals of acute treatment are to prevent potentially life-threatening cardiac
disturbances, shift ... potassium into ... eliminate excess potassium ... , changes on ECG ... , and Table 3 summarizes
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 Characteristics of Commonly Used Phosphate Binders Aluminum - Potent and effective - Useful for
Used Phosphate Binders ... Lower risk of hypercalcemia ... #Phosphate #Binders ... #Table #Comparison ... #Pharmacology #
Lactated Ringers (LR) vs Normal Saline (NS) - Comparison Composition of LR: • Sodium 130 mEq/L •
Saline (NS) - Comparison ... 130 mEq/L • Potassium ... Is Dangerous in Hyperkalemia ... transcellular shift ... #pharmacology #
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