20 results
Adrenal Insufficiency Differential Diagnosis Algorithm
Clinical suspicion: Weakness, fatigue, nausea, musculoskeletal pain, dizziness, volume depletion, abdominal pain,
Differential Diagnosis ... Weakness, fatigue, nausea ... hyponatremia, hyperkalemia ... likely: • High ... #Algorithm #endocrinology
Causes of Hypercalcemia
Parathyroid hormone–dependent
Primary hyperparathyroidism
Familial hypocalciuric hypercalcemia
Lithium-associated
Tertiary hyperparathyroidism
Genetic disorders (e.g., multiple endocrine neoplasia type 1 or
Causes of Hypercalcemia ... Genetic disorders (e.g ... thyrotoxicosis, adrenal insufficiency ... #Causes #Differential ... #Diagnosis #Endocrinology
Hyperkalemia - Differential Diagnosis Framework

PseudoHyperkalemia:
 • Lab error
 • Traumatic venipuncture
 • Hemolysis, thrombocytosis, leukocytosis
 •
Diagnosis Framework ... phlebotomy High ... Intracellular Shift ... deficiency • Renal insufficiency ... #causes #potassium
Adrenal Insufficiency - Diagnosis and Management Summary
Primary Adrenal Insufficiency:
Most Common Cause in the US: Autoimmune Adrenalitis
Other
: Most Common Cause ... ketoconazole, etomidate) Symptoms ... Hyperkalemia is ... Give 250 mcg of ... #Management #Endocrinology
Hyperkalemia - Differential Diagnosis Framework

PseudoHyperkalemia:
 • Lab error
 • Traumatic venipuncture
 • Hemolysis, thrombocytosis, leukocytosis
 •
Diagnosis Framework ... phlebotomy High ... Intracellular Shift ... deficiency • Renal insufficiency ... #causes #potassium
Primary Adrenal Insufficiency
Addison's Disease - Damage of the adrenal glands with lack of cortisol, androgens and
: Most Common Causes ... Serum DHEAS Diagnosis ... Administer 250 mcg ... addisons #disease #endocrinology ... #diagnosis #signs
Adrenal Insufficiency Diagnosis Algorithm - Evaluation of HPA Axis Response to ACTH

Early am cortisol < 3
Adrenal Insufficiency ... unclear (often the case ... Stim test is 250 mcg ... Measure ACTH: - High ... Stimulation #Test #Endocrinology
Causes of Hyperkalemia - Reduced Excretion - Differential Diagnosis Algorithm

Reduced flow through distal nephron - TTKG
Causes of Hyperkalemia ... - Differential Diagnosis ... • Low EABV (e.g ... ARB • Adrenal insufficiency ... #Algorithm #Causes
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
immature blasts and high ... WBC count cause ... hydration - Hyperkalemia ... unless worrisome EKG ... Syndrome #TLS #diagnosis
Intraoperative Cardiac Ischaemia - Guidelines for Crises in Anaesthesia

If the patient is unconscious, signs of cardiac
is conscious, symptoms ... Have a high index ... CM5 continuous ECG ... Intraoperative #Checklist ... #Diagnosis #Management