14 results
Mechanisms of Drug-Induced Hyperkalemia 
 • Direct renin inhibitor (Aliskiren)
 • Renin release inhibition (NSAIDs, Beta-Blockers)
• Increased EC ... shift of K (Succinylcholine ... #differential #diagnosis ... #pathophysiology ... #pharmacology #
Hyperkalemia - Management Algorithm
 • IV calcium
 • IV insulin and glucose and/or salbutamolt
 • Consider
potassium and ECG ... blocks, QRS axis shift ... #potassium #high ... #diagnosis #management ... #algorithm #treatment
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
immature blasts and high ... WBC count cause ... hydration - Hyperkalemia ... unless worrisome EKG ... Syndrome #TLS #diagnosis
Rhabdomyolysis - Differential Diagnosis and Management Summary

Trauma:
 • Immobilization, Crush iniury, Compartment syndrome, Electrical injury
Exertional:
 •
- Differential Diagnosis ... Dermatomyositis) AKI - Pathophysiology ... Shift of extracellular ... Dialysis for severe hyperkalemia ... Management #Summary #causes
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Disease, PRES Pathophysiology ... autoantibodies that will cause ... Lumbar Puncture, EEG ... Treatment: ... Induction Rx: high-dose
Premature Ventricular Complexes (PVC's) - Summary Framework

Why PVCs?  Can be the first manifestation of cardiac
Hypomagnesemia • Hypokalemia ... percent PVCs/day • High ... Differential Diagnosis ... tachyarrhythmias High-risk ... more intensive treatment
Evaluation and Management of Hypokalemia

Hypokalemia is often asymptomatic. Evaluation begins with a search for warning signs
warranting urgent treatment ... electrocardiography (ECG ... Most cases of hypokalemia-induced ... transcellular shifts ... #Diagnosis #Hypokalemia
The crusade against “Ab”Normal Saline continues.  This is a non-physiologic fluid that can harm our
we introduce a high ... causes Hyperkalemia ... The high CL- content ... criticalcare #management #diagnosis ... #treatment #pharmacology
Sarcoidosis - Diagnosis and Management Summary
Epidemiology
1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
Sarcoidosis - Diagnosis ... Epidemiology 1) High ... survival is 93-95% Pathophysiology ... hyperphosphatemia, hypercalcemia ... (e.g. incidental
Stiff Person Syndrome (SPS) - Diagnosis and Management Summary

Epidemiology:
 • Prevalence: 1-2 cases per million -
Prevalence: 1-2 cases ... Person Syndrome Pathophysiology ... , diaphoresis, high ... : • High index ... #Management #treatment