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differential causes anemia cell chronic daytime disorders electrophoresis eosinophil eosinophilia excessive hypercoagulable indications macrocytic microcytic oncology plasmacytoma protein serum sleepiness
Causes of Excessive Daytime Sleepiness - Differential Diagnosis Algorithm Insufficient Sleep • Poor Sleep Hygiene • Insomnia
- Differential Diagnosis ... Algorithm Insufficient ... Shift Work) Sleep ... Excessive #Daytime #Fatigue ... #Algorithm #Causes
Causes of Fatigue - Differential Diagnosis Algorithm Endocrine • Hypo/Hyperthyroidism • Diabetes • Pituitary Insufficiency • Adrenal
- Differential Diagnosis ... Algorithm Endocrine ... Liver Failure • Hypercalcemia ... Neoplastic / Hematologic ... • Drug Abuse (e.g
Approach to the Hypercoagulable State Arterial thromboembolism → Cardiac rhythm monitoring, Echocardiogram, Vascular imaging → Test for APS, particularly
• Provoked (e.g ... - No other workup ... Hypercoagulable #Workup ... #hematology #diagnosis ... #algorithm #hematology
Eosinophil Disorders Testing Algorithm INDICATIONS FOR TESTING: • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
Disorders Testing Algorithm ... evaluation or workup ... signs or symptoms (eg ... #Differential #diagnosis ... #hematology #eosinophilia
Anemia Diagnostic Algorithm Mean corpuscular (cell) volume (MCV): Average RBC size. Under 80 = microcytic. Between 80-95
Anemia Diagnostic ... Algorithm Mean ... of substrate (e.g ... #Diagnosis #Workup ... #Hematology #Microcytic
Indications for Serum Protein Electrophoresis (SPEP) • Suspected multiple myeloma, Waldenström's macroglobulinemia, primary amyloidosis, or related
suspected • Hypercalcemia ... possible malignancy (e.g ... associated weight loss, fatigue ... Electrophoresis #SPEP #Hematology ... #Diagnosis
Solitary Cell Plasmacytoma What? • Plasma cell neoplasms can present as a single lesion (solitary plasmacytoma) • In 3%
red bone marrow, e.g ... Diagnosis? ... CRAB - no anemia, hypercalcemia ... EMD myeloma Diagnostic ... #Workup #Hematology
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