7 results
Low Alkaline Phosphatase - Hypophosphatasia 

Is Low Alkaline Phosphatase Of Clinical Importance?

ALP enzyme- Discovered in 1923
Low
Low Alkaline Phosphatase ... fractures of feet, thigh ... collection with EDTA Pathophysiology ... Hyperlipidemia - Hypercalcemia ... Hyophosphatasia #hepatology
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Erythematosus (SLE ... Disease, PRES Pathophysiology ... Lumbar Puncture, EEG ... Induction Rx: high-dose ... Erythematosus #SLE
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... immature blasts and high ... hydration - Hyperkalemia ... unless worrisome EKG ... diagnosis #management #hematology
Causes of Hyperkalemia
l. Pseudohyperkalemia
  A Cellular efflux; thrombocytosis, erythrocytosis, leukocytosis, in vitro hemolysis
  B.
extracellular shift ... erythematosus (SLE ... Tubulointerstitial diseases: SLE ... Differential #Diagnosis #High ... #Potassium #Classification
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
complements and a high ... Skin Disease Classification ... • Malignancy (e.g ... . hematologic) ... vein thrombosis Hematologic
TAFRO

TAFRO syndrome was first described in 2010, standing for:
- Thrombocytopenia
- Anasarca
- Fever
- Reticulin fibrosis
- Organomegaly

TAFRO syndrome
erythematosus (SLE ... cell lymphoma Pathophysiology ... Thrombocytopenia - Elevated alkaline ... Glucocorticoid, high ... diagnosis #management #rheumatology
Hepatorenal Syndrome (HRS)

Definition:
• Functional, potentially reversible kidney impairment.
• Occurs in advanced liver disease: cirrhosis, severe alcoholic
Pathophysiology: ... Classification: ... liver insult (e.g ... Prognosis: • High ... Hepatorenal #Syndrome #Hepatology