8 results
Mechanisms of Drug-Induced Hyperkalemia 
 • Direct renin inhibitor (Aliskiren)
 • Renin release inhibition (NSAIDs, Beta-Blockers)
• Increased EC ... shift of K (Succinylcholine ... #differential #diagnosis ... #pathophysiology ... #pharmacology #potassium
Hyperkalemia - Management Algorithm
 • IV calcium
 • IV insulin and glucose and/or salbutamolt
 • Consider
Hyperkalemia - Management ... and ECG changes ... blocks, QRS axis shift ... #potassium #high ... #diagnosis #management
Low Alkaline Phosphatase - Hypophosphatasia 

Is Low Alkaline Phosphatase Of Clinical Importance?

ALP enzyme- Discovered in 1923
Low
fractures of feet, thigh ... • Pernicious anemia ... collection with EDTA Pathophysiology ... Hyperlipidemia - Hypercalcemia ... Hyophosphatasia #hepatology
Bandemia Overview

Normal: < 1%
Clinically significant: > 10%

Band neutrophils are slightly less mature than segmented neutrophils and
Left Shift: • ... Metamyelocyte (Left Shift ... with moderate and high ... neutrophil #WBC #CBC #hematology ... #pathophysiology
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
immature blasts and high ... hydration - Hyperkalemia ... unless worrisome EKG ... Syndrome #TLS #diagnosis ... #management #hematology
Causes of Hyperkalemia
l. Pseudohyperkalemia
  A Cellular efflux; thrombocytosis, erythrocytosis, leukocytosis, in vitro hemolysis
  B.
Causes of Hyperkalemia ... extracellular shift ... ), sickle cell anemia ... #Differential #Diagnosis ... #High #Potassium
Blood Product Transfusions One Pager Summary
Type and screen - determines blood type and detects in recipient
High mortality. ... Hypocalcemia, Hyperkalemia ... products contain potassium ... #Transfusions #diagnosis ... #management #hematology
Hemophagocytic Lymphohistiocytosis (HLH)

High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
Lymphohistiocytosis (HLH) High ... - Persistent high ... - Cytopenias (anemia ... Pathophysiology ... #Management #Hematology