10 results
Digoxin Pharmacology and Pathophysiology
1) Na/K ATPase Pump - Digoxin works by directly binding to and inhibiting
and Pathophysiology ... - Hyperkalemia ( ... high potassium levels ... (or low potassium ... #cardiology
Hyperkalemia - Differential Diagnosis Framework

PseudoHyperkalemia:
 • Lab error
 • Traumatic venipuncture
 • Hemolysis, thrombocytosis, leukocytosis
 •
phlebotomy High ... : • Digoxin ... • Recent IV potassium ... Intracellular Shift ... #high #nephrology
Hyperkalemia - Differential Diagnosis Framework

PseudoHyperkalemia:
 • Lab error
 • Traumatic venipuncture
 • Hemolysis, thrombocytosis, leukocytosis
 •
phlebotomy High ... : • Digoxin ... • Recent IV potassium ... Intracellular Shift ... #high #nephrology
Hyperkalemia Management
Pseudohyperkalemia: 1. Hemolyzed sample 2. Blood drawn from a site/line where potassium or TPN is
Hyperkalemia Management ... site/line where potassium ... minutes-hour) -Shift ... or dialysis • SLOW ... #high
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
immature blasts and high ... , Elevated Cr, Low ... hydration - Hyperkalemia ... unless worrisome EKG ... diagnosis #management #hematology
Blood Transfusion Reactions

Immune Mediated:
 • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
High mortality. ... Hypocalcemia, Hyperkalemia ... products contain potassium ... Hypothermia: Due to low ... diagnosis #management #hematology
Blood Product Transfusions One Pager Summary
Type and screen - determines blood type and detects in recipient
High mortality. ... Hypocalcemia, Hyperkalemia ... products contain potassium ... Hypothermia: Due to low ... diagnosis #management #hematology
Premature Ventricular Complexes (PVC's) - Summary Framework

Why PVCs?  Can be the first manifestation of cardiac
Hypomagnesemia • Hypokalemia ... Substances • Digoxin ... classified as: • Low ... percent PVCs/day • High ... #differential #cardiology
Causes of Hyperkalemia
l. Pseudohyperkalemia
  A Cellular efflux; thrombocytosis, erythrocytosis, leukocytosis, in vitro hemolysis
  B.
extracellular shift ... Digoxin and related ... Drug-associated: heparin, low-molecular-weight ... Differential #Diagnosis #High ... #Potassium #Classification
Intraoperative  Bradycardia - Guidelines for Crises in Anaesthesia
Bradycardia in theatre should not be treated as
Check fresh gas flow ... remifentanil, digoxin ... Also consider: high ... myocardial infarction, hyperkalaemia ... Management #Workup #Cardiology