8 results
Mechanisms of Drug-Induced Hyperkalemia 
 • Direct renin inhibitor (Aliskiren)
 • Renin release inhibition (NSAIDs, Beta-Blockers)
of Drug-Induced Hyperkalemia ... • Increased EC ... shift of K (Succinylcholine ... differential #diagnosis #pathophysiology ... #pharmacology #
Potassium-Binding Agents to Treat Hyperkalemia
Sodium zirconium cyclosilicate (Lokelma):
 • Mechanism: Preferentially captures K in exchange for
Potassium-Binding ... patients sensitive to high ... aspiration #Potassium #Binding ... medications #pharmacology ... #table #comparison
Digoxin Pharmacology and Pathophysiology
1) Na/K ATPase Pump - Digoxin works by directly binding to and inhibiting
Digoxin Pharmacology ... and Pathophysiology ... works by directly binding ... - Hyperkalemia ( ... high potassium levels
Lactated Ringers (LR) vs Normal Saline (NS) - Comparison

Composition of LR:
 • Sodium 130 mEq/L
 •
Saline (NS) - Comparison ... Is Dangerous in Hyperkalemia ... transcellular shift ... densa receives high ... #pharmacology #
Premature Ventricular Complexes (PVC's) - Summary Framework

Why PVCs?  Can be the first manifestation of cardiac
Hypomagnesemia • Hypokalemia ... percent PVCs/day • High ... Findings: • Broad ... fibrillation Complications ... tachyarrhythmias High-risk
The crusade against “Ab”Normal Saline continues.  This is a non-physiologic fluid that can harm our
we introduce a high ... causes Hyperkalemia ... , a complication ... The high CL- content ... diagnosis #treatment #pharmacology
Sarcoidosis - Diagnosis and Management Summary
Epidemiology
1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
Epidemiology 1) High ... survival is 93-95% Pathophysiology ... hyperphosphatemia, hypercalcemia ... of diagnosis (e.g ... incidental CXR finding
Bulimia Nervosa: Complications
GASTROINTESTINAL
 • Dehydration & inability to digest food -> Constipation
 • Recurrent vomiting exposes
Bulimia Nervosa: Complications ... ENDOCRINE • Binging ... on foods high in ... ) • Overall: hypokalemia ... #pathophysiology