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diagnosis management medications buprenorphine hematology potassium signs treatment addiction antifungals binders binding bulimianervosa coccidioides coccidioidomycosis complications differential druginduced effect effects
Mechanisms of Drug-Induced Hyperkalemia • Direct renin inhibitor (Aliskiren) • Renin release inhibition (NSAIDs, Beta-Blockers)
of Drug-Induced Hyperkalemia ... • Increased EC ... shift of K (Succinylcholine ... differential #diagnosis #pathophysiology ... #pharmacology #
Potassium-Binding Agents to Treat Hyperkalemia Sodium zirconium cyclosilicate (Lokelma): • Mechanism: Preferentially captures K in exchange for
Agents to Treat Hyperkalemia ... to moderate); hypokalemia ... patients sensitive to high ... #medications #pharmacology ... #table #comparison
Vasopressors Table Rough properties by Target Receptor, Heart Rate/Inotropy, Systemic Vascular Resistance, Cardiac Output, Blood Pressure,
Vasopressors Table ... - Dopamine, high ... Vasopressors #Properties #Table ... #Pharmacology # ... Effect #Management #Comparison
TRALI vs TACO - Transfusion Reactions TRALI: • Epidemiology: 0.1% of transfused patientsl • Risk factors: Critical
blood donor • Pathophysiology ... ARDS to explain symptoms ... transfusion • Pathophysiology ... hematology #diagnosis #comparison ... #table
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... immature blasts and high ... Spontaneous if high ... hydration - Hyperkalemia ... unless worrisome EKG
Medications for the Treatment of Hyperkalemia The goals of acute treatment are to prevent potentially life-threatening cardiac
the Treatment of Hyperkalemia ... disturbances, shift ... intervention are symptoms ... , changes on ECG ... , and Table 3 summarizes
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 Lactated Ringers (LR) vs Normal Saline (NS) - Comparison Composition of LR: • Sodium 130 mEq/L •
Saline (NS) - Comparison ... Is Dangerous in Hyperkalemia ... transcellular shift ... densa receives high ... #pharmacology #
Sarcoidosis - Diagnosis and Management Summary Epidemiology 1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
Epidemiology 1) High ... survival is 93-95% Pathophysiology ... hyperphosphatemia, hypercalcemia ... of diagnosis (e.g ... Self-limiting, chronic but stable
Opioid Use Disorder Medications - Pharmacokinetics Buprenorphine is a partial mu-opioid receptor agonist with low intrinsic activity,
intrinsic activity, high ... margin of safety in pharmacology ... the sublingual tablet ... Pharmacokinetics #Comparison ... #Table #Pharmacology
What are the different types of buprenorphine? Though predominantly used as a sublingual film, buprenorphine can also
formulations (eg ... prevent an opioid high ... #Pharmacology #Buprenorphine ... Formulations #Types #Comparison ... #Table #Suboxone
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