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management differential neurology medications potassium signs symptoms algorithm brash bulimianervosa cardiology causes cerebritis cns complexes complications criticalcare crystalloids diuresis diuretics
Mechanisms of Drug-Induced Hyperkalemia • Direct renin inhibitor (Aliskiren) • Renin release inhibition (NSAIDs, Beta-Blockers)
• Increased EC ... shift of K (Succinylcholine ... #differential #diagnosis ... #pathophysiology ... #pharmacology #
BRASH Syndrome B - Bradycardia R - Renal failure A - AV nodal blockade S - Shock H - Hyperkalemia Typical ECG
BRASH Syndrome ... Typical ECG ... ) BRASH Treatment ... #diagnosis #management ... #pathophysiology
Hyperkalemia - Management Algorithm • IV calcium • IV insulin and glucose and/or salbutamolt • Consider
potassium and ECG ... blocks, QRS axis shift ... #potassium #high ... #diagnosis #management ... #algorithm #treatment
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... immature blasts and high ... hydration - Hyperkalemia ... unless worrisome EKG ... #TLS #diagnosis
Rhabdomyolysis - Differential Diagnosis and Management Summary Trauma: • Immobilization, Crush iniury, Compartment syndrome, Electrical injury Exertional: •
- Differential Diagnosis ... iniury, Compartment syndrome ... Dermatomyositis) AKI - Pathophysiology ... Shift of extracellular ... Dialysis for severe hyperkalemia
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Demyelinating Syndrome ... Disease, PRES Pathophysiology ... Lumbar Puncture, EEG ... Treatment: ... Induction Rx: high-dose
Stiff Person Syndrome (SPS) - Diagnosis and Management Summary Epidemiology: • Prevalence: 1-2 cases per million -
Pathophysiology ... , diaphoresis, high ... • High index of ... Treatment: • ... #Management #treatment
Premature Ventricular Complexes (PVC's) - Summary Framework Why PVCs? Can be the first manifestation of cardiac
Inherited arrhythmia syndromes ... syndrome, ARVC) ... Hypomagnesemia • Hypokalemia ... percent PVCs/day • High ... more intensive treatment
Posterior Reversible Encephalopathy Syndrome (PRES) Overview Clinico-Radiological Syndrome, characterized by: • Headache • Seizures • Altered mental
Blood transfusion, Hypercalcemia ... Etiology: • Pathophysiology ... • EEG: With persistent ... epilepticus Treatment ... underlying cause • Treatment
Sarcoidosis - Diagnosis and Management Summary Epidemiology 1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
Sarcoidosis - Diagnosis ... Epidemiology 1) High ... survival is 93-95% Pathophysiology ... hyperphosphatemia, hypercalcemia ... (e.g. incidental
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