8 results
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... immature blasts and high ... Spontaneous if high ... hydration - Hyperkalemia ... unless worrisome EKG
Mechanisms of Drug-Induced Hyperkalemia 
 • Direct renin inhibitor (Aliskiren)
 • Renin release inhibition (NSAIDs, Beta-Blockers)
of Drug-Induced Hyperkalemia ... • Increased EC ... shift of K (Succinylcholine ... differential #diagnosis #pathophysiology ... #pharmacology #
Tumor Lysis Syndrome
An acute, life-threatening condition that appears within 7 days of starting cytotoxic therapies in
Tumor Lysis Syndrome ... cytotoxic therapies in high-burden ... ) occur in high ... malignancies Treatments ... with Ca only if EKG
Hyperkalemia - Management Algorithm
 • IV calcium
 • IV insulin and glucose and/or salbutamolt
 • Consider
Hyperkalemia - Management ... potassium and ECG ... blocks, QRS axis shift ... #potassium #high ... management #algorithm #treatment
Lactated Ringers (LR) vs Normal Saline (NS) - Comparison

Composition of LR:
 • Sodium 130 mEq/L
 •
Saline (NS) - Comparison ... Is Dangerous in Hyperkalemia ... transcellular shift ... densa receives high ... #pharmacology #
Hyperkalemia Management
Pseudohyperkalemia: 1. Hemolyzed sample 2. Blood drawn from a site/line where potassium or TPN is
Hyperkalemia Management ... minutes-hour) -Shift ... @AnnKumfer #Hyperkalemia ... #Management #treatment ... #potassium #high
The crusade against “Ab”Normal Saline continues.  This is a non-physiologic fluid that can harm our
we introduce a high ... causes Hyperkalemia ... The high CL- content ... management #diagnosis #treatment ... #pharmacology #
Overview of antifungal agents benefits, weaknesses, and adverse effects in the treatment of Coccidioidomycosis.
Fluconazole - Low
effects in the treatment ... /tolerable • High ... Voriconazole - High ... #antifungals #comparison ... #table #pharmacology