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diagnosis causes algorithm high nephrology management treatment arb classification constipation druginduced hypertension hypokalemia indications initiation k kdigo low monitoring pathophysiology
Mechanisms of Drug-Induced Hyperkalemia • Direct renin inhibitor (Aliskiren) • Renin release inhibition (NSAIDs, Beta-Blockers)
Angiotensin-converting enzyme (ACE ... shift of K (Succinylcholine ... #differential # ... #pharmacology #potassium ... #medications #druginduced
Hypokalemia - Differential Diagnosis Algorithm Transcellular Shift: • Alkalosis • ↑ beta-2 adrenergic simulation • Erythropoiesis
Hypokalemia - Differential ... Transcellular Shift ... Thyrotoxicosis Medications ... #Differential # ... nephrology #low #potassium
Causes of Hyperkalemia Hyperkalemia is caused by excess potassium intake, impaired potassium excretion, or transcellular shifts. The
caused by excess potassium ... intake, impaired potassium ... transcellular shifts ... renal function, medication ... #Differential #
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 Constipation - Differential Diagnosis Algorithm Diet/Lifestyle • Fibre • Calories • Fluid • Exercise • Psychosocial Medications •
Constipation - Differential ... Psychosocial Medications ... Neurally Active Medications ... Aluminum, Calcium, Potassium ... • Hypercalcemia
Hyperkalemia - Differential Diagnosis Framework PseudoHyperkalemia: • Lab error • Traumatic venipuncture • Hemolysis, thrombocytosis, leukocytosis •
Hyperkalemia - Differential ... • NSAIDs • ACE ... Intracellular Shift ... Medications 2. ... #differential #
Medications for the Treatment of Hyperkalemia The goals of acute treatment are to prevent potentially life-threatening cardiac
Medications for ... disturbances, shift ... , changes on ECG ... Table 3 summarizes medications ... #Management #Medications
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 Hyperkalemia - Differential Diagnosis Framework PseudoHyperkalemia: • Lab error • Traumatic venipuncture • Hemolysis, thrombocytosis, leukocytosis •
Hyperkalemia - Differential ... • NSAIDs • ACE ... Intracellular Shift ... Medications 2. ... #differential #
ACEI or ARB Initiation Hyperkalemia: - Review concurrent drugs - Moderate potassium Intake - Consider: diuretics, sodium
ACEI or ARB Initiation ... Hyperkalemia: ... drugs - Moderate potassium ... Reassess concomitant medications ... (e.g., diuretics
Emergent Hyperkalemia Treatment Algorithm ECG changes, weakness, K+ >6.5 Or renal insufficiency with K >5.5 with cellular
Emergent Hyperkalemia ... Treatment Algorithm ECG ... cardiac membrane Shift ... treatment Remove potassium ... offending agent (ACE-I
Causes of Hyperkalemia - Differential Diagnosis Framework • Cellular Shift: - Exercise
- Differential ... Framework • Cellular Shift ... hyperosmolality - Medications ... #Differential # ... Diagnosis #Causes #potassium
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