12 results
Key Characteristics of Old and New Potassium-Binding Agents

- Dr. Edgar V. Lerma https://twitter.com/edgarvlermamd

#Potassium #Binding #KBinders #Kayexelate
Potassium #Binding #KBinders ... Kayexelate #Comparison #Table ... #Pharmacology # ... Patiromer #HyperKalemia ... #Nephrology #Agents
Potassium-Binding Agents to Treat Hyperkalemia
Sodium zirconium cyclosilicate (Lokelma):
 • Mechanism: Preferentially captures K in exchange for
and sodium • Dosing ... magnesium • Dosing ... #medications #pharmacology ... #table #comparison ... #binders
Phosphate binders - quick reference chart of maximum daily dose. Most patients with CKD will require
since they are not able ... restricted due to hypercalcemia ... Only* #CKD #Nephrology ... Hyperphosphatemia #Dose #Dosing ... #Pharmacology #
Potassium Binders for Management of Hyperkalemia
 • SPS - Sodium polystyrene sulfonate
 • Patiromer (veltassa)
 •
Potassium Binders ... Management of Hyperkalemia ... #treatment #pharmacology ... #table #comparison ... #nephrology
Characteristics of Commonly Used Phosphate Binders 
Aluminum 
 - Potent and effective 
 - Useful for
Used Phosphate Binders ... #Phosphate #Binders ... #Table #Comparison ... #Pharmacology # ... Nephrology
Hyperkalemia - Differential Diagnosis Framework

PseudoHyperkalemia:
 • Lab error
 • Traumatic venipuncture
 • Hemolysis, thrombocytosis, leukocytosis
 •
Hyperkalemia - Differential ... Clenching of fist during ... Intracellular Shift ... #differential # ... potassium #high #nephrology
Hyperkalemia - Differential Diagnosis Framework

PseudoHyperkalemia:
 • Lab error
 • Traumatic venipuncture
 • Hemolysis, thrombocytosis, leukocytosis
 •
Hyperkalemia - Differential ... Clenching of fist during ... Intracellular Shift ... #differential # ... potassium #high #nephrology
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary

Causes of Rhabdomyolysis:
 • Trauma:
	- Immobilization
	- Crush injury
	- Compartment
Rhabdomyolysis - Differential ... Shift of extracellular ... fluid/Lactated ringers ... per day until stable ... causes #treatment #nephrology
Reflex Testing - Causes of Hyporeflexia and Hyperreflexia
Focal Hyporeflexia: 
 • Radiculopathy, Mononeuropathy, Polyneuropathy, Acute stroke,
Hyporeflexia: • Hypercalcemia ... polyneuropathy (e.g ... Testing #Causes #differential ... #diagnosis #table ... #neurology
Causes of Hyperkalemia - Intercellular Shift - Differential Diagnosis Algorithm
Transcellular Shift - Appropriate renal excretion (GFR,
Causes of Hyperkalemia ... Intercellular Shift ... - Differential ... • Cell Lysis (e.g ... IntercellularShift #Nephrology