23 results
Key Characteristics of Old and New Potassium-Binding Agents

- Dr. Edgar V. Lerma https://twitter.com/edgarvlermamd

#Potassium #Binding #KBinders #Kayexelate
of Old and New Potassium-Binding ... edgarvlermamd #Potassium ... KBinders #Kayexelate #Comparison ... #Table #Pharmacology ... #Patiromer #HyperKalemia
Potassium-Binding Agents to Treat Hyperkalemia
Sodium zirconium cyclosilicate (Lokelma):
 • Mechanism: Preferentially captures K in exchange for
Agents to Treat Hyperkalemia ... patients sensitive to high ... #Binding #Hyperkalemia ... #medications #pharmacology ... #table #comparison
Hyperkalemia Management Algorithm
 • Treat the cause & optimize hemodynamics and ventilation
 • Reconsider treatment leadingto
Hyperkalemia Management ... • Treat the cause ... treatment leadingto hyperkalemia ... / Removal #Hyperkalemia ... #high
Potassium Binders for Management of Hyperkalemia
 • SPS - Sodium polystyrene sulfonate
 • Patiromer (veltassa)
 •
Potassium Binders ... Management of Hyperkalemia ... Binders #Management #Hyperkalemia ... #treatment #pharmacology ... #table #comparison
Hyperkalemia - Differential Diagnosis Framework

PseudoHyperkalemia:
 • Lab error
 • Traumatic venipuncture
 • Hemolysis, thrombocytosis, leukocytosis
 •
Hyperkalemia - Differential ... Suspicion for Hyperkalemia ... Drugs Causing Hyperkalemia ... cantaloupe #hyperkalemia ... #potassium #high
Hyperkalemia - Differential Diagnosis Framework

PseudoHyperkalemia:
 • Lab error
 • Traumatic venipuncture
 • Hemolysis, thrombocytosis, leukocytosis
 •
Hyperkalemia - Differential ... Suspicion for Hyperkalemia ... Drugs Causing Hyperkalemia ... images/12834 #hyperkalemia ... #potassium #high
Characteristics of Commonly Used Phosphate Binders 
Aluminum 
 - Potent and effective 
 - Useful for
Lower risk of hypercalcemia ... range - Lack of hypercalcemia ... requirements - Lack of hypercalcemia ... range - Lack of hypercalcemia ... #Comparison #Pharmacology
Considerations for Crystalloids - 0.9% NS vs LR vs Plasma-Lyte
 - Causes hyperkalemia?
 - Safe to
hyperkalemia? ... patients with hyperkalemia ... Update: AKI in NS row ... #Crystalloids #pharmacology ... #indications #comparison
Causes of Hyperkalemia - Differential Diagnosis Framework
 • Cellular Shift:
   - Exercise
Causes of Hyperkalemia ... Framework • Cellular Shift ... Hemolysis • Pseudo hyperkalemia ... Medicine @ucsdim #Hyperkalemia ... #potassium #high
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary

Causes of Rhabdomyolysis:
 • Trauma:
	- Immobilization
	- Crush injury
	- Compartment
• LDH ↑ • Hyperkalemia ... /Late - Hypercalcemia ... Shift of extracellular ... Monitor potassium ... Dialysis for severe hyperkalemia