11 results
Potassium-Binding Agents to Treat Hyperkalemia
Sodium zirconium cyclosilicate (Lokelma):
 • Mechanism: Preferentially captures K in exchange for
Potassium-Binding ... Agents to Treat Hyperkalemia ... K; also binds magnesium ... #Binding #Hyperkalemia ... #medications #pharmacology
Hypomagnesemia - Etiologies by Mechanism

Decreased GI Uptake 
 - Poor dietary intake (particularly common in alcoholics)
abnormalities - Hypercalcemia ... Differential #Diagnosis #Low ... #Magnesium #Table ... Classification #Causes ... #Workup #hypomg
Digoxin Pharmacology and Pathophysiology
1) Na/K ATPase Pump - Digoxin works by directly binding to and inhibiting
Digoxin Pharmacology ... Pump - Digoxin works ... intracellular calcium causes ... - Hyperkalemia ( ... (or low potassium
Here’s a review of the Renin-Angiotensin-Aldosterone system (RAAS)

This is a very common pathway that clinicians should
aldosterone which does a lot ... sodium, which causes ... inhibiting drug classes ... avoid harmful hyperkalemia ... ReninAngiotensinAldosteroneSystem #RAAS #Pharmacology
Hyperkalemia - Diagnosis and Management - GrepMed Handbook

S/Sx: Most pts asymptomatic. Weakness, cramping, nausea, paresthesias, palpitations,
Hyperkalemia - Diagnosis ... acidosis) • Low ... emcrit.org/ibcc/hyperkalemia ... management of hyperkalemia ... #Hyperkalemia
Lactated Ringers (LR) vs Normal Saline (NS) - Comparison

Composition of LR:
 • Sodium 130 mEq/L
 •
130 mEq/L • Potassium ... Is Dangerous in Hyperkalemia ... transcellular shift ... • Saline Causes ... NS #comparison #pharmacology
Causes of Hyperkalemia
l. Pseudohyperkalemia
  A Cellular efflux; thrombocytosis, erythrocytosis, leukocytosis, in vitro hemolysis
  B.
Causes of Hyperkalemia ... extracellular shift ... axis; T risk of hyperkalemia ... antiphospholipid syndrome #Hyperkalemia ... Diagnosis #High #Potassium
Malignant Hyperthermia Crisis - Guidelines for Crises in Anaesthesia
Unexplained increase in ETCO2 AND tachycardia AND increased
other, more common causes ... with dantrolene Hyperkalaemia ... Arrhythmias: magnesium ... Intraoperative #Checklist ... Diagnosis #Management #Workup
Cardiac Arrest - Guidelines for Crises in Anaesthesia

The probable cause is one or more of: something
Increase fresh gas flow ... Hypovolaemia Hypo/hyperkalaemia ... CardiacArrest #Checklist ... Intraoperative #Checklist ... Diagnosis #Management #Workup
Intraoperative  Bradycardia - Guidelines for Crises in Anaesthesia
Bradycardia in theatre should not be treated as
Check fresh gas flow ... Consider known drug causes ... myocardial infarction, hyperkalaemia ... Intraoperative #Checklist ... Diagnosis #Management #Workup