27 results
diagnosis differential causes potassium nephrology hypokalemia cardiology algorithm management classification comparison hepatology high low medications pediatrics peds pulmonary syndrome table
Gitelman Syndrome Pathophysiology Gitelman Syndrome is a rare autosomal recessive salt-losing tubulopathy with a prevalence of 1-
Gitelman Syndrome ... Pathophysiology ... recessive salt-losing ... H+ secretion → Hypokalemia ... #Syndrome #Pathophysiology
Mechanisms of Drug-Induced Hyperkalemia • Direct renin inhibitor (Aliskiren) • Renin release inhibition (NSAIDs, Beta-Blockers)
of Drug-Induced Hyperkalemia ... • Increased EC shift ... MunerMohamed1 #hyperkalemia ... differential #diagnosis #pathophysiology ... #pharmacology #
Hypokalemia Differential Diagnosis Algorithm Low intake • poor oral intake Renal loss • Medication • Hypomagnesemia •
Hypokalemia Differential ... tubular acidosis • Gitelman's ... Transcellular shift ... amzn.to/2LmUODZ #Hypokalemia
Causes of Hypokalemia - Differential Diagnosis Algorithm Increased Loss - Increased GI Loss - Increased Urinary
Causes of Hypokalemia ... Transcellular Shift ... Refeeding Syndrome #Hypokalemia ... potassium #low #pathophysiology
Potassium-Binding Agents to Treat Hyperkalemia Sodium zirconium cyclosilicate (Lokelma): • Mechanism: Preferentially captures K in exchange for
Agents to Treat Hyperkalemia ... and sodium • Dosing ... binds magnesium • Dosing ... and calcium • Dosing ... #medications #pharmacology
Beta-Blockers in Cirrhosis • Pathophysiology • Indications: Prevention of decompensation, Prevention of first variceal bleeding,
in Cirrhosis • Pathophysiology ... gastropathy • Dosing ... hepatology #management #pharmacology ... #indications #dosing
Hyperkalemia - Differential Diagnosis Framework PseudoHyperkalemia: • Lab error • Traumatic venipuncture • Hemolysis, thrombocytosis, leukocytosis •
Hyperkalemia - Differential ... Clenching of fist during ... Suspicion for Hyperkalemia ... Drugs Causing Hyperkalemia ... Intracellular Shift
Algorithm for patients with hypokalemia on the basis of the potassium-to-creatinine ratio in the urine Urine K+
patients with hypokalemia ... creatinine) • Cell shift ... Bartter syndrome, Gitelman ... syndrome #hypokalemia
Drugs that Impair Renal Potassium Excretion Decreased ENaC channel function: Amiloride, Triamterene, Pentamidine Decreased Aldosterone Synthesis: Heparin,
happypillsrx/ #Hyperkalemia ... #Pathophysiology ... #Pharmacology #
Gitelman Syndrome Overview What? • Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter • Gitelman's syndrome
Gitelman Syndrome ... hypokalemic salt-losing ... cotransporter • Gitelman's ... nephrology #management #pathophysiology ... #Hypokalemia
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