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differential high nephrology anesthesiology checklist intraoperative rhabdomyolysis treatment workup algorithm bradycardia cardiacarrest cardiology classification druginduced encephalopathy erythema evaluation hypokalemia medications
Mechanisms of Drug-Induced Hyperkalemia • Direct renin inhibitor (Aliskiren) • Renin release inhibition (NSAIDs, Beta-Blockers)
Mechanisms of Drug-Induced ... • Increased EC shift ... #differential #diagnosis ... pathophysiology #pharmacology ... #potassium #medications
Causes of Hyperkalemia Pseudohyperkalemia - Tourniquet use - Hemolysis (in vitro) - Leukocytosis - Thrombocytosis Intra- to extracellular
Causes of Hyperkalemia ... shift - Acidosis ... drugs - Transfusion ... Renal failure* - Drugs—potassium-sparing ... #Causes #diagnosis
Hyperkalemia - Differential Diagnosis Framework PseudoHyperkalemia: • Lab error • Traumatic venipuncture • Hemolysis, thrombocytosis, leukocytosis •
Diagnosis Framework ... reactions Common Drugs ... • Recent IV potassium ... Intracellular Shift ... #causes #potassium
Hyperkalemia - Differential Diagnosis Framework PseudoHyperkalemia: • Lab error • Traumatic venipuncture • Hemolysis, thrombocytosis, leukocytosis •
Diagnosis Framework ... reactions Common Drugs ... • Recent IV potassium ... Intracellular Shift ... #causes #potassium
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary Causes of Rhabdomyolysis: • Trauma: - Immobilization - Crush injury - Compartment
Summary Causes ... - Toxins - Drugs ... Shift of extracellular ... Monitor potassium ... #Management #causes
Rhabdomyolysis - Differential Diagnosis and Management Summary Trauma: • Immobilization, Crush iniury, Compartment syndrome, Electrical injury Exertional: •
Drugs (Statins), ... Shift of extracellular ... Monitor potassium ... Dialysis for severe hyperkalemia ... #causes #treatment
Cardiac Arrest - Guidelines for Crises in Anaesthesia The probable cause is one or more of: something
Hypovolaemia Hypo/hyperkalaemia ... : Vagal tone Drug ... Anesthesiology #Anesthesia ... Intraoperative #Checklist #Diagnosis ... #Management #Workup
Intraoperative Bradycardia - Guidelines for Crises in Anaesthesia Bradycardia in theatre should not be treated as
Consider known drug ... myocardial infarction, hyperkalaemia ... Anesthesiology #Anesthesia ... Intraoperative #Checklist #Diagnosis ... #Management #Workup
Causes of Hyperkalemia l. Pseudohyperkalemia A Cellular efflux; thrombocytosis, erythrocytosis, leukocytosis, in vitro hemolysis B.
Causes of Hyperkalemia ... extracellular shift ... #Differential #Diagnosis ... #High #Potassium ... Classification #Causes
Evaluation and Management of Hypokalemia Hypokalemia is often asymptomatic. Evaluation begins with a search for warning signs
Evaluation and Management ... Most cases of hypokalemia-induced ... transcellular shifts ... depletion impedes potassium ... #Diagnosis #Hypokalemia
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