11 results
diagnosis management differential algorithm table binders criticalcare medications nephrology pathophysiology rhabdomyolysis binding chf clinical crystalloids digoxin druginduced effects evaluation heartfailure
Mechanisms of Drug-Induced Hyperkalemia • Direct renin inhibitor (Aliskiren) • Renin release inhibition (NSAIDs, Beta-Blockers)
of Drug-Induced Hyperkalemia ... • Increased EC shift ... #hyperkalemia ... pathophysiology #pharmacology ... #potassium #medications
Hyperkalemia Management Algorithm • Treat the cause & optimize hemodynamics and ventilation • Reconsider treatment leadingto
• Treat the cause ... • Reconsider treatment ... and parenteral potassium ... Intracellular K+ Shift ... #potassium #high
Potassium-Binding Agents to Treat Hyperkalemia Sodium zirconium cyclosilicate (Lokelma): • Mechanism: Preferentially captures K in exchange for
Potassium-Binding ... ); nausea, vomiting ... of aspiration #Potassium ... #medications #pharmacology ... #table #comparison
Potassium Binders for Management of Hyperkalemia • SPS - Sodium polystyrene sulfonate • Patiromer (veltassa) •
Potassium Binders ... Management of Hyperkalemia ... cyclosilicate #Potassium ... #treatment #pharmacology ... #table #comparison
Digoxin Pharmacology and Pathophysiology 1) Na/K ATPase Pump - Digoxin works by directly binding to and inhibiting
Digoxin Pharmacology ... intracellular calcium causes ... - Hyperkalemia ( ... , in states of hypokalemia ... Pathophysiology #cardiology
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary Causes of Rhabdomyolysis: • Trauma: - Immobilization - Crush injury - Compartment
Management Summary Causes ... Shift of extracellular ... Treatment of underlying ... Monitor potassium ... Diagnosis #Management #causes
Rhabdomyolysis - Differential Diagnosis and Management Summary Trauma: • Immobilization, Crush iniury, Compartment syndrome, Electrical injury Exertional: •
Shift of extracellular ... Monitor potassium ... Dialysis for severe hyperkalemia ... Management #Summary #causes ... #treatment
Lactated Ringers (LR) vs Normal Saline (NS) - Comparison Composition of LR: • Sodium 130 mEq/L •
Saline (NS) - Comparison ... 130 mEq/L • Potassium ... Is Dangerous in Hyperkalemia ... transcellular shift ... #pharmacology #
Evaluation and Management of Hypokalemia Hypokalemia is often asymptomatic. Evaluation begins with a search for warning signs
warranting urgent treatment ... Most cases of hypokalemia-induced ... transcellular shifts ... Identification and treatment ... depletion impedes potassium
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 It is important to recognize Acute Decompensated Heart Failure (ADHF) as more than just simply a
the determined cause ... algorithm #management #cardiology ... #treatment #table ... #foamed #heartfailure ... icu #clinical #pharmacology
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