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diagnosis differential nephrology hypokalemia management treatment low comparison blood cardiology criticalcare medications pathophysiology pharmacology product rhabdomyolysis transfusion binders binding classification
Causes of Hyperkalemia - Differential Diagnosis Algorithm • Increased Intake • Reduced Excretion (IV potassium with
Causes of Hyperkalemia ... Excretion (IV potassium ... Transcellular Shift ... #Hyperkalemia ... #Causes
Hyperkalemia - Differential Diagnosis Framework PseudoHyperkalemia: • Lab error • Traumatic venipuncture • Hemolysis, thrombocytosis, leukocytosis •
phlebotomy High ... • Recent IV potassium ... Intracellular Shift ... differential #diagnosis #causes ... #potassium #high
Causes of Hypokalemia - Differential Diagnosis Algorithm Increased Loss - Increased GI Loss - Increased Urinary
Causes of Hypokalemia ... Differential Diagnosis Algorithm ... Transcellular Shift ... Refeeding Syndrome #Hypokalemia ... #causes #potassium
Hyperkalemia - Differential Diagnosis Framework PseudoHyperkalemia: • Lab error • Traumatic venipuncture • Hemolysis, thrombocytosis, leukocytosis •
phlebotomy High ... • Recent IV potassium ... Intracellular Shift ... differential #diagnosis #causes ... #potassium #high
Hyperkalemia Management Algorithm • Treat the cause & optimize hemodynamics and ventilation • Reconsider treatment leadingto
Algorithm • Treat ... the cause & optimize ... and parenteral potassium ... Intracellular K+ Shift ... #high
Causes of Hypokalemia Hypokalemia results from abnormal losses, transcellular shifts, or insufficient intake (Table 1).6–8 Abnormal losses
Causes of Hypokalemia ... transcellular shifts ... insufficient intake (Table ... significantly lower potassium ... rarely the sole cause
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 Hyperkalemia Differential Diagnosis Algorithm R/O Pseudo-hyperkalemia: • Possible Lab error! Alwavs Repeat Blood sample! • Leukocytosis, Thrombocytosis:
Diagnosis Algorithm ... TTKG should be high ... Differential #Diagnosis #Algorithm ... #causes #potassium ... #high #pathophysiology
Hyperkalemia - Management Algorithm • IV calcium • IV insulin and glucose and/or salbutamolt • Consider
Hyperkalemia - Management ... Algorithm • IV ... Dialysis Serum potassium ... blocks, QRS axis shift ... #potassium #high
Potassium-Binding Agents to Treat Hyperkalemia Sodium zirconium cyclosilicate (Lokelma): • Mechanism: Preferentially captures K in exchange for
Potassium-Binding ... ); nausea, vomiting ... patients sensitive to high ... of aspiration #Potassium ... #pharmacology #table
Hypokalemia Differential Diagnosis Algorithm Hypertensive: • High Al, Low R - Primary aldosteronism • High Al, High
Hypokalemia Differential ... Diagnosis Algorithm ... Gitelman's syndrome #Hypokalemia ... #nephrology #causes ... #low #potassium
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