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diagnosis differential management treatment high nephrology medications acei antihypertensive arb bloodpressure cardiology constipation contraindications druginduced evaluation hfpef hypertension hypokalemia initiation
Emergency Management of Hyperkalemia in Adults Assess Patient - Airway Breathing Circulation Disability Exposure (ABCDE) Approach •
mmol/L - Consider cause ... clinical scenario, ECG ... Gluconate IV Shift ... Prevention - Consider cause ... #management #algorithm
Mechanisms of Drug-Induced Hyperkalemia • Direct renin inhibitor (Aliskiren) • Renin release inhibition (NSAIDs, Beta-Blockers)
of Drug-Induced Hyperkalemia ... • Increased EC ... shift of K (Succinylcholine ... #pharmacology #potassium ... #medications #druginduced
Hyperkalemia - Differential Diagnosis Framework PseudoHyperkalemia: • Lab error • Traumatic venipuncture • Hemolysis, thrombocytosis, leukocytosis •
: • CKD • Poorly ... • NSAIDs • ACE ... Intracellular Shift ... Medications 2. ... differential #diagnosis #causes
Emergent Hyperkalemia Treatment Algorithm ECG changes, weakness, K+ >6.5 Or renal insufficiency with K >5.5 with cellular
Emergent Hyperkalemia ... ECG changes, weakness ... injury, etc) ECG ... cardiac membrane Shift ... treatment Remove potassium
Constipation - Differential Diagnosis Algorithm Diet/Lifestyle • Fibre • Calories • Fluid • Exercise • Psychosocial Medications •
(e.g. ... Cation Related (e.g ... Aluminum, Calcium, Potassium ... Anticholinergic (e.g ... #Causes
Hyperkalemia - Differential Diagnosis Framework PseudoHyperkalemia: • Lab error • Traumatic venipuncture • Hemolysis, thrombocytosis, leukocytosis •
: • CKD • Poorly ... • NSAIDs • ACE ... Intracellular Shift ... Medications 2. ... differential #diagnosis #causes
Medications for the Treatment of Hyperkalemia The goals of acute treatment are to prevent potentially life-threatening cardiac
disturbances, shift ... underlying problem can ... , changes on ECG ... Figure 3 is an algorithm ... , and Table 3 summarizes
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 Hyperkalemia - Management Algorithm • IV calcium • IV insulin and glucose and/or salbutamolt • Consider
Hyperkalemia - Management ... Algorithm • IV ... depletion • Consider K+ ... and ECG changes ... blocks, QRS axis shift
Causes of Hyperkalemia - Differential Diagnosis Framework • Cellular Shift: - Exercise
Causes of Hyperkalemia ... Framework • Cellular Shift ... to Aldosterone: K ... depletion, - AKI/CKD ... #potassium #high
Compelling and Possible Contraindications to Antihypertensive Drugs Diuretics (thiazides) - Gout - Metabolic syndrome, Glucose intolerance, Pregnancy,
ARB, diabetes) ACE ... Heart failure Ca2 ... Pgp-dependent drugs (e.g ... antihypertensive #medications ... contraindications #table
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