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diagnosis differential management algorithm nephrology high hypokalemia pharmacology syndrome medications table binders hematology rhabdomyolysis adrenal binding cah cardiology classification congenitaladrenalhyperplasia
Causes of Hyperkalemia Hyperkalemia is caused by excess potassium intake, impaired potassium excretion, or transcellular shifts. The
Causes of Hyperkalemia ... is caused by excess ... potassium intake ... , impaired potassium ... transcellular shifts
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 Causes of Hyperkalemia - Differential Diagnosis Algorithm • Increased Intake • Reduced Excretion (IV potassium with
Causes of Hyperkalemia ... Excretion (IV potassium ... Transcellular Shift ... #Hyperkalemia ... Diagnosis #Algorithm #Causes
Causes of Hypokalemia - Differential Diagnosis Algorithm Increased Loss - Increased GI Loss - Increased Urinary
Causes of Hypokalemia ... Transcellular Shift ... Diagnosis #Algorithm #causes ... #potassium #low ... #pathophysiology
Hyperkalemia Treatment Options Stabilize cardiac membrane: • IV Calcium (peaks 5-10 minutes) Decrease potassium concentration: • IV Fluids Shift
Hyperkalemia Treatment ... minutes) Decrease potassium ... • IV Fluids Shift ... potassium intracellularly ... LouLectures #Hyperkalemia
Mechanisms of Drug-Induced Hyperkalemia • Direct renin inhibitor (Aliskiren) • Renin release inhibition (NSAIDs, Beta-Blockers)
of Drug-Induced Hyperkalemia ... • Increased EC shift ... MunerMohamed1 #hyperkalemia ... differential #diagnosis #pathophysiology ... #pharmacology #potassium
Hyperkalemia Management Algorithm • Treat the cause & optimize hemodynamics and ventilation • Reconsider treatment leadingto
• Treat the cause ... • Reconsider treatment ... and parenteral potassium ... Intracellular K+ Shift ... #potassium #high
Emergency Management of Hyperkalemia in Adults Assess Patient - Airway Breathing Circulation Disability Exposure (ABCDE) Approach •
Management of Hyperkalemia ... mmol/L - Consider cause ... Gluconate IV Shift ... Prevention - Consider cause ... of hyperkalaemia
Causes of Hypokalemia Hypokalemia results from abnormal losses, transcellular shifts, or insufficient intake (Table 1).6–8 Abnormal losses
Causes of Hypokalemia ... transcellular shifts ... significantly lower potassium ... rarely the sole cause ... #Differential #Causes
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 Hyperkalemia Differential Diagnosis Algorithm R/O Pseudo-hyperkalemia: • Possible Lab error! Alwavs Repeat Blood sample! • Leukocytosis, Thrombocytosis:
Hyperkalemia Differential ... Algorithm R/O Pseudo-hyperkalemia ... Diagnosis #Algorithm #causes ... #potassium #high ... #pathophysiology
Potassium-Binding Agents to Treat Hyperkalemia Sodium zirconium cyclosilicate (Lokelma): • Mechanism: Preferentially captures K in exchange for
Potassium-Binding ... constipation, diarrhea, nausea ... ); nausea, vomiting ... of aspiration #Potassium ... pharmacology #table #comparison
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