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diagnosis management differential causes lysis nephrology tumor rhabdomyolysis acute aki cancer classification hematology hypokalemia injury kidney leukostasis summary tumorlysis uricacid
Classification of Tumor Lysis Syndrome (TLS) and Treatment of Metabolic Abnormalities of TLS Laboratory TLS: • Uric
of Tumor Lysis Syndrome ... (TLS) and Treatment ... hydroxide • Hyperkalemia ... #TumorLysis #Syndrome ... #management #oncology
Tumor Lysis Syndrome An acute, life-threatening condition that appears within 7 days of starting cytotoxic therapies in
Tumor Lysis Syndrome ... malignancies Treatments ... 6L/day) • For hyperkalemia ... #Tumor #Lysis #Syndrome ... #TLS #oncology
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary Causes of Rhabdomyolysis: • Trauma: - Immobilization - Crush injury - Compartment
- Compartment syndrome ... HIV, Influenza, TSS ... or compartment syndrome ... Shift of extracellular ... Treatment of underlying
Tumor Lysis Syndrome - Workup and Management Initial workup: BMP, Serum uric acid, LDH, Urine output, Consider
Tumor Lysis Syndrome ... of the above Treatment ... of Clinical TLS ... MatthewHoMD #TLS ... diagnosis #management #oncology
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
organ damage • Treatment ... leukapheresis - TLS ... hydration - Hyperkalemia ... treatment (no calcium ... #TLS #diagnosis
Rhabdomyolysis - Differential Diagnosis and Management Summary Trauma: • Immobilization, Crush iniury, Compartment syndrome, Electrical injury Exertional: •
iniury, Compartment syndrome ... Neuroleptic malignant syndrome ... HIV, Influenza, TSS ... Shift of extracellular ... Dialysis for severe hyperkalemia
Acute Kidney Injury (AKI) in Patients with Cancer Cancer Related • Hypercalcemia • Intravenous contrast •
Cancer Related • Hypercalcemia ... malignancies Treatment ... Capillary leak syndrome ... • Tumor lysis syndrome ... #AKI #Cancer #Oncology
Causes of Hypokalemia Transcellular Shifts: - Alkalosis, Increased plasma insulin (treatment of diabetic ketoacidosis), ß-Adrenergic agonists, Hypokalemic
Causes of Hypokalemia ... Transcellular Shifts ... plasma insulin (treatment ... use), Gitelman's syndrome ... or induced) #Hypokalemia
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