59 results
Classification of Tumor Lysis Syndrome (TLS) and Treatment of Metabolic Abnormalities of TLS
Laboratory TLS:
 • Uric
of Tumor Lysis Syndrome ... (TLS) and Treatment ... Calcium ≤ 7.0 mg/dL Clinical ... Treatment of TLS ... #TumorLysis #Syndrome
Emergency Management of Hyperkalemia in Adults
Assess Patient - Airway Breathing Circulation Disability Exposure (ABCDE) Approach
 •
Management of Hyperkalemia ... guided by clinical ... scenario, ECG and ... Gluconate IV Shift ... recurrence #Hyperkalemia
Mechanisms of Drug-Induced Hyperkalemia 
 • Direct renin inhibitor (Aliskiren)
 • Renin release inhibition (NSAIDs, Beta-Blockers)
of Drug-Induced Hyperkalemia ... • Increased EC ... shift of K (Succinylcholine ... MunerMohamed1 #hyperkalemia ... pathophysiology #pharmacology
BRASH Syndrome

B - Bradycardia
R - Renal failure
A - AV nodal blockade
S - Shock
H - Hyperkalemia

Typical ECG
BRASH Syndrome ... Typical ECG ... ) BRASH Treatment ... • Aggressive treatment ... DrEricStrong #BRASH #Syndrome
Causes of Hypokalemia
Transcellular Shifts:
 - Alkalosis, Increased plasma insulin (treatment of diabetic ketoacidosis), ß-Adrenergic agonists, Hypokalemic
Transcellular Shifts ... plasma insulin (treatment ... diuresis, Bartter's syndrome ... use), Gitelman's syndrome ... excess and related syndromes
Emergent Hyperkalemia Treatment Algorithm
ECG changes, weakness, K+ >6.5 Or renal insufficiency with K >5.5 with cellular
Emergent Hyperkalemia ... ECG changes, weakness ... injury, etc) ECG ... cardiac membrane Shift ... not quickly) #Hyperkalemia
Hyperkalemia - Management Algorithm
 • IV calcium
 • IV insulin and glucose and/or salbutamolt
 • Consider
Hyperkalemia - Management ... potassium and ECG ... blocks, QRS axis shift ... , asystole #hyperkalemia ... management #algorithm #treatment
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary

Causes of Rhabdomyolysis:
 • Trauma:
	- Immobilization
	- Crush injury
	- Compartment
- Compartment syndrome ... Dermatomyositis Clinical ... or compartment syndrome ... Shift of extracellular ... Treatment of underlying
Wolff-Parkinson-White Syndrome

WPW is a congenital abnormality characterized by an abnormal accessory conduction pathway between the atria
Wolff-Parkinson-White Syndrome ... QRS interval on EKG ... The definitive treatment ... WPW #Cardiology #ECG ... #Clinical #Diagnosis
Recurrent Polymorphic VT/Torsades de Pointes - Management Algorithm
Drugs that prolong QT interval:
 • Class 1a (quinidine,
Congenital long QT Syndrome ... Hypomagnesemia • Hypokalemia ... • Hypocalcemia ... (rarely) Treatment ... • Adult: 0.5-5 mcg