31 results
Causes of Hyperkalemia

Hyperkalemia is caused by excess potassium intake, impaired potassium excretion, or transcellular shifts. The
Causes of Hyperkalemia ... is caused by excess ... potassium intake ... transcellular shifts ... renal function, medication
Mechanisms of Drug-Induced Hyperkalemia 
 • Direct renin inhibitor (Aliskiren)
 • Renin release inhibition (NSAIDs, Beta-Blockers)
of Drug-Induced Hyperkalemia ... • Increased EC ... shift of K (Succinylcholine ... #pharmacology #potassium ... #medications #druginduced
Hyperkalemia - Differential Diagnosis Framework

PseudoHyperkalemia:
 • Lab error
 • Traumatic venipuncture
 • Hemolysis, thrombocytosis, leukocytosis
 •
phlebotomy High ... Intracellular Shift ... Medications 2. ... differential #diagnosis #causes ... #potassium #high
Medications for the Treatment of Hyperkalemia
The goals of acute treatment are to prevent potentially life-threatening cardiac
Medications for ... disturbances, shift ... , changes on ECG ... Table 3 summarizes medications ... #Management #Medications
Potassium-Binding Agents to Treat Hyperkalemia
Sodium zirconium cyclosilicate (Lokelma):
 • Mechanism: Preferentially captures K in exchange for
Potassium-Binding ... ); nausea, vomiting ... patients sensitive to high ... of aspiration #Potassium ... #medications #pharmacology
Hyperkalemia - Management Algorithm
 • IV calcium
 • IV insulin and glucose and/or salbutamolt
 • Consider
Hyperkalemia - Management ... Dialysis Serum potassium ... and ECG changes ... blocks, QRS axis shift ... #potassium #high
Hyperkalemia - Differential Diagnosis Framework

PseudoHyperkalemia:
 • Lab error
 • Traumatic venipuncture
 • Hemolysis, thrombocytosis, leukocytosis
 •
phlebotomy High ... Intracellular Shift ... Medications 2. ... differential #diagnosis #causes ... #potassium #high
Constipation - Differential Diagnosis Algorithm
Diet/Lifestyle
 • Fibre
 • Calories
 • Fluid
 • Exercise
 • Psychosocial
Medications
 •
Psychosocial Medications ... Neurally Active Medications ... Aluminum, Calcium, Potassium ... Hypothyroidism • Hypokalemia ... Diagnosis #Algorithm #Causes
Drugs associated with hypokalemia and hypomagnesemia

Hypokalemia
- Shift from extracellular fluid to intracellular fluid compartment
  -
associated with hypokalemia ... - Shift from extracellular ... - Insulin (high ... hypomagnesemia #Medications ... diagnosis #nephrology #Causes
Hyperkalemia Management Algorithm
 • Treat the cause & optimize hemodynamics and ventilation
 • Reconsider treatment leadingto
• Treat the cause ... and parenteral potassium ... Intracellular K+ Shift ... Algorithm #treatment #potassium ... #high