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Hyperkalemia Hypokalemia - Differential Diagnosis and Management Algorithm

Dr Pravin Patel

#Hypokalemia #Hyperkalemia #potassium #differential #diagnosis #management
Hyperkalemia Hypokalemia ... Diagnosis and Management ... Pravin Patel #Hypokalemia ... #Hyperkalemia # ... potassium #differential
Hypokalemia - Differential Diagnosis Algorithm

Transcellular Shift:
 • Alkalosis
 • ↑ beta-2 adrenergic simulation 
 • Erythropoiesis
Hypokalemia - Differential ... Transcellular Shift ... Transcellular shifts ... MatthewHoMD #Hypokalemia ... nephrology #low #potassium
Causes of Hypokalemia - Differential Diagnosis Algorithm
Increased Loss 
 - Increased GI Loss
 - Increased Urinary
Causes of Hypokalemia ... Transcellular Shift ... Refeeding Syndrome #Hypokalemia ... Algorithm #causes #potassium
Potassium-Binding Agents to Treat Hyperkalemia
Sodium zirconium cyclosilicate (Lokelma):
 • Mechanism: Preferentially captures K in exchange for
Agents to Treat Hyperkalemia ... to moderate); hypokalemia ... Hypomagnesemia; hypokalemia ... disturbances (including hypokalemia ... #Binding #Hyperkalemia
Algorithm for patients with hypokalemia on the basis of the potassium-to-creatinine ratio in the urine
Urine K+
patients with hypokalemia ... the basis of the potassium-to-creatinine ... creatinine) • Cell shift ... syndrome #hypokalemia ... #urine #potassium
Classification of Tumor Lysis Syndrome (TLS) and Treatment of Metabolic Abnormalities of TLS
Laboratory TLS:
 • Uric
8.0 mg/dL • Potassium ... other symptomatic hypocalcemia ... hydroxide • Hyperkalemia ... treatment • Hypocalcemia ... TLS #diagnosis #management
Medications for the Treatment of Hyperkalemia
The goals of acute treatment are to prevent potentially life-threatening cardiac
the Treatment of Hyperkalemia ... disturbances, shift ... provoke rebound hypokalemia ... algorithm for the management ... #Management #Medications
Hyperkalemia Treatment Options
Stabilize cardiac membrane:
 • IV Calcium (peaks 5-10 minutes)
Decrease potassium concentration:
 • IV Fluids
Shift
Hyperkalemia Treatment ... minutes) Decrease potassium ... • IV Fluids Shift ... LouLectures #Hyperkalemia ... #management #potassium
Hyperkalemia Management Algorithm
 • Treat the cause & optimize hemodynamics and ventilation
 • Reconsider treatment leadingto
Hyperkalemia Management ... treatment leadingto hyperkalemia ... Intracellular K+ Shift ... / Removal #Hyperkalemia ... #high
Checklist Approach to Hypokalemia

Consider risk factors for arrhythmia:
 - EKG changes (especially QT prolongation)
 - Digoxin
Checklist Approach to Hypokalemia ... route = severe hypokalemia ... /hr for severe hypokalemia ... #Checklist #Hypokalemia ... #Management #CriticalCare