28 results
Hypokalemia - Differential Diagnosis Algorithm

Transcellular Shift:
 • Alkalosis
 • ↑ beta-2 adrenergic simulation 
 • Erythropoiesis
Hypokalemia - Differential ... Transcellular Shift ... MatthewHoMD #Hypokalemia ... Diagnosis #Algorithm #nephrology ... #low #potassium
Potassium-Binding Agents to Treat Hyperkalemia
Sodium zirconium cyclosilicate (Lokelma):
 • Mechanism: Preferentially captures K in exchange for
Potassium-Binding ... to moderate); hypokalemia ... Side Effects: Hypomagnesemia ... ; hypokalemia; constipation ... disturbances (including hypokalemia
Hypomagnesemia - Differential Diagnosis
Renal Causes of Hypomagnesemia - Familial:
Bartter syndrome and Gitelman syndrome, Isolated recessive hypomagnesemia,
Hypomagnesemia - ... with secondary, hypocalcemia ... pentamidine), Hypercalcemia ... diagnosis #causes #nephrology ... #magnesium #low
Checklist Approach to Hypokalemia

Consider risk factors for arrhythmia:
 - EKG changes (especially QT prolongation)
 - Digoxin
Checklist Approach to Hypokalemia ... Concomitant severe hy pomagnesemia ... route = severe hypokalemia ... /hr for severe hypokalemia ... #Checklist #Hypokalemia
Potassium Electrolyte Repletion
If patient also has hypomagnesemia, replete magnesium before repleting potassium
Oral:
 • Pills (ask pharmacy
Potassium Electrolyte ... patient also has hypomagnesemia ... , replete magnesium ... before repleting potassium ... Repletion #management #hypokalemia
Drugs associated with hypokalemia and hypomagnesemia

Hypokalemia
- Shift from extracellular fluid to intracellular fluid compartment
  -
associated with hypokalemia ... Hypokalemia ... - Shift from extracellular ... panitumumab) #Drugs #hypokalemia ... differential #diagnosis #nephrology
Evaluation and Management of Hypokalemia

Hypokalemia is often asymptomatic. Evaluation begins with a search for warning signs
Hypokalemia is ... transcellular shifts ... of concurrent hypomagnesemia ... important because magnesium ... depletion impedes potassium
Causes of Hypokalemia - Differential Diagnosis Algorithm
Defining the cause of hypokalemia starts by measuring urinary K
Causes of Hypokalemia ... Defining the cause of hypokalemia ... hypokalemia • ... Cushing's syndrome #hypokalemia ... #potassium
Gitelman Syndrome Overview

What?
• Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter
• Gitelman's syndrome
Family history of hypokalemia ... • Unexplained hypokalemia ... pressure Labs: • Hypokalemia ... • Magnesium ... pathophysiology #Hypokalemia
Hyperkalemia Treatment Options
Stabilize cardiac membrane:
 • IV Calcium (peaks 5-10 minutes)
Decrease potassium concentration:
 • IV Fluids
Shift
Hyperkalemia Treatment ... minutes) Decrease potassium ... • IV Fluids Shift ... LouLectures #Hyperkalemia ... #nephrology