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diagnosis differential hyperkalemia management nephrology algorithm classification pharmacology rhabdomyolysis acidosis binders cardiology drugs effects elevation hypomagnesemia hypomg k lactate lactated
Potassium-Binding Agents to Treat Hyperkalemia Sodium zirconium cyclosilicate (Lokelma): • Mechanism: Preferentially captures K in exchange for
Potassium-Binding ... patients sensitive to high ... #Binding #Hyperkalemia ... #medications #pharmacology ... #table #comparison
Hyperkalemia Management Algorithm • Treat the cause & optimize hemodynamics and ventilation • Reconsider treatment leadingto
• Treat the cause ... • Reconsider treatment ... and parenteral potassium ... Intracellular K+ Shift ... #potassium #high
Hyperkalemia - Differential Diagnosis Framework PseudoHyperkalemia: • Lab error • Traumatic venipuncture • Hemolysis, thrombocytosis, leukocytosis •
Intracellular Shift ... - Tumor lysis syndrome ... Medications 2. ... differential #diagnosis #causes ... #potassium #high
Hyperkalemia - Differential Diagnosis Framework PseudoHyperkalemia: • Lab error • Traumatic venipuncture • Hemolysis, thrombocytosis, leukocytosis •
Intracellular Shift ... - Tumor lysis syndrome ... Medications 2. ... differential #diagnosis #causes ... #potassium #high
Hyperkalemia - Management Algorithm • IV calcium • IV insulin and glucose and/or salbutamolt • Consider
Hyperkalemia - Management ... Widening of QRS complex ... blocks, QRS axis shift ... #potassium #high ... management #algorithm #treatment
Drugs associated with hypokalemia and hypomagnesemia Hypokalemia - Shift from extracellular fluid to intracellular fluid compartment -
- Shift from extracellular ... - Insulin (high ... renal Fanconi syndrome ... hypomagnesemia #Medications ... diagnosis #nephrology #Causes
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary Causes of Rhabdomyolysis: • Trauma: - Immobilization - Crush injury - Compartment
Management Summary Causes ... - Compartment syndrome ... Shift of extracellular ... Monitor potassium ... Diagnosis #Management #causes
Rhabdomyolysis - Differential Diagnosis and Management Summary Trauma: • Immobilization, Crush iniury, Compartment syndrome, Electrical injury Exertional: •
Shift of extracellular ... Monitor potassium ... Dialysis for severe hyperkalemia ... Management #Summary #causes ... #treatment
Premature Ventricular Complexes (PVC's) - Summary Framework Why PVCs? Can be the first manifestation of cardiac
Inherited arrhythmia syndromes ... (e.g., long QT syndrome ... heart disease Causes ... Hypomagnesemia • Hypokalemia ... more intensive treatment
Hyperkalemia - Diagnosis and Management - GrepMed Handbook S/Sx: Most pts asymptomatic. Weakness, cramping, nausea, paresthesias, palpitations,
Etiology: • Medications ... only if no clear cause ... STOP offending medications ... : • K-Binding ... #potassium #nephrology
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