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diagnosis differential hyperkalemia management nephrology algorithm classification pharmacology rhabdomyolysis acidosis druginduced elevation encephalopathy helicobacter hematology hpylori hypomagnesemia hypomg lactate lactic
Causes of Hypokalemia - Differential Diagnosis Algorithm Increased Loss - Increased GI Loss - Increased Urinary
Causes of Hypokalemia ... Transcellular Shift ... - Refeeding Syndrome ... #potassium #low ... #pathophysiology
Drugs associated with hypokalemia and hypomagnesemia Hypokalemia - Shift from extracellular fluid to intracellular fluid compartment -
- Shift from extracellular ... - Insulin (high ... renal Fanconi syndrome ... #Medications #differential ... diagnosis #nephrology #Causes
Mechanisms of Drug-Induced Hyperkalemia • Direct renin inhibitor (Aliskiren) • Renin release inhibition (NSAIDs, Beta-Blockers)
Mechanisms of Drug-Induced ... • Increased EC shift ... differential #diagnosis #pathophysiology ... #pharmacology #potassium ... #medications #druginduced
Hyperkalemia - Differential Diagnosis Framework PseudoHyperkalemia: • Lab error • Traumatic venipuncture • Hemolysis, thrombocytosis, leukocytosis •
reactions Common Drugs ... Intracellular Shift ... - Tumor lysis syndrome ... Medications 2. ... #potassium #high
Hyperkalemia - Differential Diagnosis Framework PseudoHyperkalemia: • Lab error • Traumatic venipuncture • Hemolysis, thrombocytosis, leukocytosis •
reactions Common Drugs ... Intracellular Shift ... - Tumor lysis syndrome ... Medications 2. ... #potassium #high
Hyperkalemia Management Algorithm • Treat the cause & optimize hemodynamics and ventilation • Reconsider treatment leadingto
• Treat the cause ... • Reconsider treatment ... and parenteral potassium ... Intracellular K+ Shift ... #potassium #high
Rhabdomyolysis - Differential Diagnosis and Management Summary Trauma: • Immobilization, Crush iniury, Compartment syndrome, Electrical injury Exertional: •
Drugs (Statins), ... Shift of extracellular ... Monitor potassium ... Dialysis for severe hyperkalemia ... Management #Summary #causes
Causes of Hypokalemia Transcellular Shifts: - Alkalosis, Increased plasma insulin (treatment of diabetic ketoacidosis), ß-Adrenergic agonists, Hypokalemic
Causes of Hypokalemia ... Transcellular Shifts ... plasma insulin (treatment ... Conn's, Liddle's), Drugs ... #Causes #differential
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary Causes of Rhabdomyolysis: • Trauma: - Immobilization - Crush injury - Compartment
Management Summary Causes ... - Toxins - Drugs ... Shift of extracellular ... Monitor potassium ... Diagnosis #Management #causes
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... immature blasts and high ... WBC count cause ... Spontaneous if high ... hydration - Hyperkalemia
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