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diagnosis hyperkalemia causes differential nephrology algorithm erythematosus lupus lysis oncology rhabdomyolysis summary systemic tumor behcet cerebritis classification cns disease hematology
Classification of Tumor Lysis Syndrome (TLS) and Treatment of Metabolic Abnormalities of TLS Laboratory TLS: • Uric
of Tumor Lysis Syndrome ... (TLS) and Treatment ... 8.0 mg/dL • Potassium ... Treatment of TLS ... #management #oncology
Hyperkalemia Management Algorithm • Treat the cause & optimize hemodynamics and ventilation • Reconsider treatment leadingto
Hyperkalemia Management ... • Reconsider treatment ... Intracellular K+ Shift ... #treatment #potassium ... #high
Hyperkalemia - Management Algorithm • IV calcium • IV insulin and glucose and/or salbutamolt • Consider
Hyperkalemia - Management ... Dialysis Serum potassium ... blocks, QRS axis shift ... #potassium #high ... #algorithm #treatment
Hyperkalemia - Differential Diagnosis Framework PseudoHyperkalemia: • Lab error • Traumatic venipuncture • Hemolysis, thrombocytosis, leukocytosis •
phlebotomy High ... Intracellular Shift ... - Tumor lysis syndrome ... insufficiency/Failure • SLE ... #high #nephrology
Rhabdomyolysis - Differential Diagnosis and Management Summary Trauma: • Immobilization, Crush iniury, Compartment syndrome, Electrical injury Exertional: •
Diagnosis and Management ... HIV, Influenza, TSS ... Shift of extracellular ... Monitor potassium ... Dialysis for severe hyperkalemia
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
immature blasts and high ... Spontaneous if high ... hydration - Hyperkalemia ... #TLS #diagnosis ... #management #hematology
Hyperkalemia - Differential Diagnosis Framework PseudoHyperkalemia: • Lab error • Traumatic venipuncture • Hemolysis, thrombocytosis, leukocytosis •
phlebotomy High ... Intracellular Shift ... - Tumor lysis syndrome ... insufficiency/Failure • SLE ... #high #nephrology
Tumor Lysis Syndrome An acute, life-threatening condition that appears within 7 days of starting cytotoxic therapies in
Tumor Lysis Syndrome ... ) occur in high ... malignancies Treatments ... #TLS #oncology ... #management #UricAcid
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary Causes of Rhabdomyolysis: • Trauma: - Immobilization - Crush injury - Compartment
Framework and Management ... HIV, Influenza, TSS ... Shift of extracellular ... Monitor potassium ... Differential #Diagnosis #Management
Systemic Lupus Erythematosus - Summary Antinuclear (ANA) - 95% - Initial screening test Anti-dsDNA - 50% • Associated
block • Sjogren syndrome ... severe disease Treatment ... Severe disease- high ... Summary #diagnosis #rheumatology ... #management
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