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diagnosis differential management hyperkalemia nephrology oncology rhabdomyolysis classification hematology k leukostasis summary tumorlysis uricacid
Classification of Tumor Lysis Syndrome (TLS) and Treatment of Metabolic Abnormalities of TLS Laboratory TLS: • Uric
Classification of Tumor ... Lysis Syndrome ... (TLS) and Treatment ... 8.0 mg/dL • Potassium ... Treatment of TLS
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Lysis Syndrome ... WBC count cause ... Lysis Syndrome: ... hydration - Hyperkalemia ... #Lysis #Syndrome
Hyperkalemia - Differential Diagnosis Framework PseudoHyperkalemia: • Lab error • Traumatic venipuncture • Hemolysis, thrombocytosis, leukocytosis •
Intracellular Shift ... Transfusion reaction - Tumor ... lysis syndrome ... Medications 2. ... #potassium #high
Hyperkalemia - Differential Diagnosis Framework PseudoHyperkalemia: • Lab error • Traumatic venipuncture • Hemolysis, thrombocytosis, leukocytosis •
Intracellular Shift ... Transfusion reaction - Tumor ... lysis syndrome ... Medications 2. ... #potassium #high
Tumor Lysis Syndrome An acute, life-threatening condition that appears within 7 days of starting cytotoxic therapies in
Tumor Lysis Syndrome ... ) occur in high ... malignancies Treatments ... #Lysis #Syndrome ... #TLS #oncology
Causes of Hyperkalemia - Differential Diagnosis Framework • Cellular Shift: - Exercise
Causes of Hyperkalemia ... Framework • Cellular Shift ... hyperosmolality - Medications ... Increased production: TLS ... #potassium #high
Hyperkalemia - Diagnosis and Management - GrepMed Handbook S/Sx: Most pts asymptomatic. Weakness, cramping, nausea, paresthesias, palpitations,
Etiology: • Medications ... Acidosis, Cell Lysis ... (TLS, rhabdo/crush ... only if no clear cause ... #potassium #nephrology
Rhabdomyolysis - Differential Diagnosis and Management Summary Trauma: • Immobilization, Crush iniury, Compartment syndrome, Electrical injury Exertional: •
HIV, Influenza, TSS ... Shift of extracellular ... Monitor potassium ... Dialysis for severe hyperkalemia ... Management #Summary #causes
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary Causes of Rhabdomyolysis: • Trauma: - Immobilization - Crush injury - Compartment
Management Summary Causes ... HIV, Influenza, TSS ... Shift of extracellular ... Monitor potassium ... Diagnosis #Management #causes
Causes of Hyperkalemia l. Pseudohyperkalemia A Cellular efflux; thrombocytosis, erythrocytosis, leukocytosis, in vitro hemolysis B.
Causes of Hyperkalemia ... extracellular shift ... Rapid tumor lysis ... antiphospholipid syndrome ... #Potassium #Classification
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