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diagnosis differential causes hyponatremia management potassium epilepticus gitelman hyperkalemia hypotonic intercellularshift neurology pathophysiology pediatrics physiologic rhabdomyolysis seizure status table urine
Hypokalemia - Differential Diagnosis Algorithm Transcellular Shift: • Alkalosis • ↑ beta-2 adrenergic simulation • Erythropoiesis
Diagnosis Algorithm ... Transcellular Shift ... • Refeeding syndrome ... vomiting) • Low ... #nephrology #low
Algorithm for patients with hypokalemia on the basis of the potassium-to-creatinine ratio in the urine Urine K+
Algorithm for patients ... with hypokalemia ... creatinine) • Cell shift ... #differential #algorithm ... #diagnosis #nephrology
Causes of Hypokalemia - Differential Diagnosis Algorithm Decreased intake (rare cause in isolation) GI loss - Urine loss
Causes of Hypokalemia ... Differential Diagnosis Algorithm ... Transcellular shift ... #Nephrology #Differential ... #Diagnosis #Algorithm
Modified Hyponatremia Algorithm Hypertonic Hyponatremia: Hyperglycemia, Mannitol, Urologic irrigants Hypotonic Hyponatremia: • ADH ON (UOsm > 100):
ON (UNa < 30): Hypovolemia ... Cirrhosis, Nephrotic syndrome ... Primary polydipsia, Low ... #diagnosis #sodium ... #nephrology
Gitelman Syndrome Overview What? • Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter • Gitelman's syndrome
thiazide-sensitive sodium ... alkalosis • Normal or low ... tachycardia • Seizures ... Rhabdomyolysis Treatment ... #diagnosis #nephrology
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary Causes of Rhabdomyolysis: • Trauma: - Immobilization - Crush injury - Compartment
- Compartment syndrome ... exertion/training - Seizures ... or compartment syndrome ... Shift of extracellular ... #nephrology
Physiologic Approach to Hypotonic Hyponatremia The next time you have a case of hypotonic hyponatremia, give the
normal volume-based algorithm ... can be high or low ... Present (Uosm ≥100): Hypovolemia ... Cirrhosis, Nephrotic syndrome ... #nephrology
Causes of Hyperkalemia - Intercellular Shift - Differential Diagnosis Algorithm Transcellular Shift - Appropriate renal excretion (GFR,
Causes of Hyperkalemia ... Intercellular Shift ... , TTKG, distal flow ... Tumor Lysis Syndrome ... IntercellularShift #Nephrology
Hyponatremia - Differential Algorithm Isotonic Hyponatremia: Hyperlipidemia, Hyperproteinemia, Recent TURP Hypotonic Hyponatremia: • Hypovolemia: Diuretics/Nephropathies, Vomiting, Diarrhea,
- Differential Algorithm ... Hyponatremia: • Hypovolemia ... Cirrhosis, Nephrotic Syndrome ... diagnosis #causes #nephrology ... #sodium #low
Management of Convulsive Status Epilepticus in children Stabilization Phase (Seizure 0-5 minutes): • Check and maintain ABC
• Give high flow ... IV Thiopental Sodium ... #Management #neurology ... #pediatrics #peds ... #algorithm
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