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management table diagnosis differential comparison nephrology causes algorithm covid19 high idsa cardiology pharmacotherapy hypokalemia tuberculosis anesthesia anesthesiology coronavirus diabetes endocrinology
Mechanisms of Drug-Induced Hyperkalemia • Direct renin inhibitor (Aliskiren) • Renin release inhibition (NSAIDs, Beta-Blockers)
Mechanisms of Drug-Induced ... Hyperkalemia ... • Increased EC shift ... pathophysiology #pharmacology ... #potassium #medications
Hypokalemia - Differential Diagnosis Algorithm Transcellular Shift: • Alkalosis • ↑ beta-2 adrenergic simulation • Erythropoiesis
Hypokalemia - Differential ... Transcellular Shift ... Thyrotoxicosis Medications ... Transcellular shifts ... nephrology #low #potassium
Causes of Hyperkalemia Hyperkalemia is caused by excess potassium intake, impaired potassium excretion, or transcellular shifts. The
caused by excess potassium ... intake, impaired potassium ... transcellular shifts ... renal function, medication ... adapt to excess potassium
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 Medications for the Treatment of Hyperkalemia The goals of acute treatment are to prevent potentially life-threatening cardiac
Medications for ... the Treatment of ... disturbances, shift ... Table 3 summarizes medications ... #Management #Medications
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 Hyperkalemia Treatment Options Stabilize cardiac membrane: • IV Calcium (peaks 5-10 minutes) Decrease potassium concentration: • IV Fluids Shift
Hyperkalemia Treatment ... minutes) Decrease potassium ... • IV Fluids Shift ... potassium intracellularly ... LouLectures #Hyperkalemia
Topical drug formulations, comparison and considerations #pharmacology #table #medications #comparison #drugs #treatment #pharmacotherapy #dermatology
Topical drug formulations ... considerations #pharmacology ... #table #medications ... #comparison #drugs ... #treatment #pharmacotherapy
Potassium-Binding Agents to Treat Hyperkalemia Sodium zirconium cyclosilicate (Lokelma): • Mechanism: Preferentially captures K in exchange for
Potassium-Binding ... and sodium • Dosing ... and calcium • Dosing ... of aspiration #Potassium ... #medications #pharmacology
Synthroid color-coded tablets and initial dosing #pharmacology #dosing #medications #drugs #overview
tablets and initial dosing ... #pharmacology ... #dosing #medications ... #drugs #overview
Hyperkalemia - Differential Diagnosis Framework PseudoHyperkalemia: • Lab error • Traumatic venipuncture • Hemolysis, thrombocytosis, leukocytosis •
Clenching of fist during ... reactions Common Drugs ... • Recent IV potassium ... Intracellular Shift ... Medications 2.
Veltassa (Patiromer) MECHANISM: Potassium Binder INDICATION: Treatment of Hyperkalemia FORMULATION: Powder for oral suspension DOSING: 8.4
INDICATION: Treatment ... oral suspension DOSING ... from other oral drugs ... this from other drugs ... #Pharmacology
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