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diagnosis management differential nephrology algorithm clinical comparison criticalcare foamed medications rhabdomyolysis anesthesia anesthesiology anthracycline binders binding bradycardia cardiotoxicity checklist chemotherapy
Potassium-Binding Agents to Treat Hyperkalemia Sodium zirconium cyclosilicate (Lokelma): • Mechanism: Preferentially captures K in exchange for
Potassium-Binding ... patients sensitive to high ... of aspiration #Potassium ... #medications #pharmacology ... #table #comparison
Hyperkalemia Management Algorithm • Treat the cause & optimize hemodynamics and ventilation • Reconsider treatment leadingto
• Treat the cause ... • Reconsider treatment ... and parenteral potassium ... Intracellular K+ Shift ... #potassium #high
Hyperkalemia - Differential Diagnosis Framework PseudoHyperkalemia: • Lab error • Traumatic venipuncture • Hemolysis, thrombocytosis, leukocytosis •
Clenching of fist during ... phlebotomy High ... Intracellular Shift ... differential #diagnosis #causes ... #potassium #high
Hyperkalemia - Differential Diagnosis Framework PseudoHyperkalemia: • Lab error • Traumatic venipuncture • Hemolysis, thrombocytosis, leukocytosis •
Clenching of fist during ... phlebotomy High ... Intracellular Shift ... differential #diagnosis #causes ... #potassium #high
Digoxin Pharmacology and Pathophysiology 1) Na/K ATPase Pump - Digoxin works by directly binding to and inhibiting
Digoxin Pharmacology ... intracellular calcium causes ... - Hyperkalemia ( ... high potassium levels ... Pathophysiology #cardiology
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary Causes of Rhabdomyolysis: • Trauma: - Immobilization - Crush injury - Compartment
Management Summary Causes ... Shift of extracellular ... Monitor potassium ... per day until stable ... Diagnosis #Management #causes
Rhabdomyolysis - Differential Diagnosis and Management Summary Trauma: • Immobilization, Crush iniury, Compartment syndrome, Electrical injury Exertional: •
Shift of extracellular ... Monitor potassium ... Dialysis for severe hyperkalemia ... Management #Summary #causes ... #treatment
Lactated Ringers (LR) vs Normal Saline (NS) - Comparison Composition of LR: • Sodium 130 mEq/L •
130 mEq/L • Potassium ... Is Dangerous in Hyperkalemia ... transcellular shift ... densa receives high ... NS #comparison #pharmacology
Intraoperative Bradycardia - Guidelines for Crises in Anaesthesia Bradycardia in theatre should not be treated as
remember to tailor treatment ... Consider known drug causes ... Also consider: high ... myocardial infarction, hyperkalaemia ... Management #Workup #Cardiology
Diuretics and Agents Regulating Renal Excretion Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide) • Glaucoma • Epilepsy • Altitude
Loop Diuretics; High-Ceiling ... Hyponatremia • Hypercalcemia ... Kidney stones caused ... Tolvaptan) • Treatment ... #Medications #Table
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