15 results
Alkaline Phosphatase (ALP) Elevation - Differential Diagnosis Algorithm

ALP:
 - Enzymes that catalyze hydrolysis of organic phosphate
Algorithm ALP ... Cholangitis (PBC ... - PSC - Other ... biliary diseases ... #Algorithm #hepatology
Primary Biliary Cirrhosis - Diagnosis Algorithm
Symptoms: Fatigue, Pruritus, Right upper quadrant discomfort
Signs: Jaundice, Xanthelasmata, Hepatomegaly
Associated history:
PBC if 2/3 criteria ... Liver biopsy findings ... consistent with PBC ... #PBC #Primary ... #Diagnosis #Algorithm
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
Autoimmune hepatitis, PBC ... , PSC, IgG4, HLH ... stone, Malignancy, PBC ... , PSC, Cystic fibrosis ... #algorithm #hepatology
Causes of Acute Liver Injury - Differential Diagnosis
Hepatocellular - Liver Parenchyma
 • Infectious: Hepatitis C, A,
- Differential Diagnosis ... Malignancy, 1° PBC ... , 1° PSC, Cystic ... Causes #Acute #algorithm ... #hepatology
Abnormal Liver Function Tests - Differential Diagnosis Algorithm for Transaminitis
Hepatocellular Pattern (ALT or AST > ALP):
Diagnosis Algorithm ... Ducts - PBC ... , PSC, Alcoholic ... stricture, PSC, ... #diagnosis #hepatology
Primary Biliary Cirrhosis (PBC) - Summary

PBC Epidemiology:
 • Female:Male 9:1
 • Common European descent
 • Age:
Cirrhosis (PBC) ... - Summary PBC ... 30-65 years PBC ... failure PBC ... • Fatigue PBC
The 6 C’s of Primary Sclerosing Cholangitis (PSC)
PSC is a chronic, cholestatic, immune-mediated disease characterized by
to multi-focal biliary ... asymptomatic at diagnosis ... colorectal and hepato-biliary ... #Cholangitis #diagnosis ... management #summary #Hepatology
Elevated Liver Enzymes - Differential Diagnosis Algorithm
Severe ALT > 15x ULN
 • Viral
 • Drugs/Toxins
 •
Elevated Liver Enzymes ... Algorithm Severe ... • Cholestatic disease ... Bile Ducts • PSC ... Duct Stone • Biliary
Autoantibodies and their Disease Associations
ANA - Non-specific; common in SLE, autoimmune hepatitis
Anti-CCP, Rheumatoid factor - RA
Anti-dsDNA
Dermatomyositis Anti-LKM (liver ... Anti-gp210 - Primary biliary ... cirrhosis (PBC) ... #diagnosis #table ... #rheumatology #
Abnormal liver function tests algorithm.
 This figure details the initial response to abnormal liver blood tests.
tests algorithm ... include extrahepatic biliary ... body mass index; FBC ... disease; T2DM, ... #Hepatology #Liver