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differential hematology causes testing gastroenterology dermatology iron laboratory nutrition oncology thrombocytosis acid acidosis adrenal alkalosis alopecia approach arthritis b12 base
Gastrointestinal Evaluation of Iron Deficiency Anemia In patients with anemia, diagnose iron deficiency if: • Ferritin <
Gastrointestinal Evaluation ... with anemia, diagnose ... inflammation or chronic ... for celiac disease ... #Evaluation #workup
Anemia - Underproduction Diagnostic Algorithm - Iron deficiency anemia - Anemia of chronic inflammation - Anemia
Diagnostic Algorithm ... - Anemia of chronic ... kidney disease ... Probable bone marrow disorder ... #differential #workup
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
Algorithm Spurious ... • Rheumatic disorders ... • Celiac disease ... malignancy • Iron deficiency ... anemia #Thrombocytosis
Overall Approach to Anemia - Differential Diagnosis Algorithm Blood Loss • Acute Bleed - Normocytic / Normochromic
- Differential Diagnosis ... Algorithm Blood ... RBCs on Smear • Chronic ... • Anemia of Chronic ... Disease • Marrow
Causes of Iron Deficiency • Diet: ↓ Intake, e.g. vegan, Malnutrition, Polyphenol / tannins, ↓ Vitamin
Drugs, H pylori, Celiac ... disease (↑ hepcidin ... Iron metabolism disorders ... #differential #diagnosis ... #anemia #nutrition
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia ... - Differential Diagnosis ... Algorithm • Sickle ... Consider RBC membrane disorder ... #Algorithm #workup
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Normal Blood Smear •
- Differential Diagnosis ... Algorithm Normal ... • Dietary Deficiency ... • Small Bowel Disorder ... Liver Function Tests
Chronic Diarrhea - Workup Osmotic: • Consider food diary and trial avoiding certain foods or meds, Consider
Chronic Diarrhea ... - Workup Osmotic ... hydrogen breath test ... disease Inflammatory ... #testing #evaluation
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
hematology for workup ... Acute hemolysis, deficiency ... anemia, Rebound ... disease, Kawasaki ... • Infections: Chronic
Nail Disorders secondary to Systemic Diseases Nail Fold Abnormality • SLE • Scleroderma • Dermatomyositis Koilonychia - Spoon-shaped
Nail Disorders secondary ... Spoon-shaped • Iron deficiency ... discoloration) • Chronic ... #Differential #Diagnosis ... #Algorithm #causes
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