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diagnosis differential hypokalemia causes hypernatremia hypophosphatemia epilepticus framework gitelman hyponatremia neurology pathophysiology pediatrics peds phosphate phosphorus potassium prs pulmonary seizure
Hypokalemia - Differential Diagnosis Algorithm Transcellular Shift: • Alkalosis • ↑ beta-2 adrenergic simulation • Erythropoiesis
Transcellular Shift ... • Refeeding syndrome ... Losses Non-renal ... losses (NG suction, diarrhea ... #nephrology #low
Hypernatremia Diagnosis and Workup Step 1 . Repeat the sodium concentration. Step 2. Check plasma osmolality. NORMAL PLASMA
Diagnosis and Workup ... Repeat the sodium ... volume loss - diarrhea ... • nephrotic syndrome ... #Algorithm #Nephrology
Workup for Hypophosphatemia - Differential Diagnosis Framework Rule out spurious hypophosphatemia: paraproteinemia, acute leukemia Measure Urine Fractional Excretion
Workup for Hypophosphatemia ... Malabsorption, Chronic diarrhea ... Transcellular Shift ... FEPO4 ≥ 5% - Renal ... #phosphate #nephrology
Hypernatremia - Differential Diagnosis Workup Algorithm 1) Check Urine Osmolality: > 600 mOsm/kg - Implies extrarenal mechanism
Differential Diagnosis Workup ... Algorithm 1) ... • Euvolemic (Low ... #Algorithm #nephrology ... #sodium
Hypophosphatemia - Differential Diagnosis Algorithm Appropriately Low Kidney Phosphate Excretion: • Decreased GI Absorption: Chronic Diarrhea, Antacids,
Appropriately Low ... Absorption: Chronic Diarrhea ... Transcellular Shift ... #nephrology #phosphorus ... #workup
Causes of Hypokalemia - Differential Diagnosis Algorithm Decreased intake (rare cause in isolation) GI loss - Urine loss
Differential Diagnosis Algorithm ... <20mmol/d • Diarrhea ... Transcellular shift ... aldosterone • Renal ... #Hypokalemia #Nephrology
Hyponatremia - Differential Algorithm Isotonic Hyponatremia: Hyperlipidemia, Hyperproteinemia, Recent TURP Hypotonic Hyponatremia: • Hypovolemia: Diuretics/Nephropathies, Vomiting, Diarrhea,
Nephropathies, Vomiting, Diarrhea ... Cirrhosis, Nephrotic Syndrome ... , Chronic Renal ... diagnosis #causes #nephrology ... #sodium #low
Pulmonary Renal Syndromes - OnePager Summary Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
life-threatening diseases ... Inflammatory eye disease ... mononeuritis multiplex WORKUP ... anti-GBM) Other tests ... #diagnosis #management
Gitelman Syndrome Overview What? • Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter • Gitelman's syndrome
alkalosis • Normal or low ... • Autoimmune disease ... Congenital chloride diarrhea ... #diagnosis #nephrology ... #management #pathophysiology
Management of Convulsive Status Epilepticus in children Stabilization Phase (Seizure 0-5 minutes): • Check and maintain ABC
Management of Convulsive ... Consider CBC, renal ... function test, ... IV Thiopental Sodium ... #peds #algorithm
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